» Articles » PMID: 33062489

First Australian Case of Good Recovery of a COVID-19 Patient With Severe Neurological Symptoms Post Prolonged Hospitalization

Overview
Journal Cureus
Date 2020 Oct 16
PMID 33062489
Citations 12
Authors
Affiliations
Soon will be listed here.
Abstract

A case of a 75-year-old man with COVID-19, severe neurological symptoms (acute stroke-like symptoms and signs and full recovery after a prolonged hospital stay), and intracranial hypertension is discussed with an in-depth review of his clinical features, biochemistry, haematology, highlighting the relationship between changes in neutrophil-lymphocyte ratio, C-reactive protein level, D-dimer level, and the clinical onset of acute ischemic stroke-like symptoms in the setting of COVID-19 and major neurological manifestations. This is the first such case reported in Australia to date. This case also illustrates the recovery of a patient with COVID-19 complicated with severe neurological symptoms (acute ischemic stroke-like symptoms) during the prolonged intensive care unit stay (at day 26) followed by slow neurorehabilitation and normal recovery from both respiratory and neurological involvement. The onset of acute stroke-like symptoms appears to be closely associated with changes of neutrophil-lymphocyte ratio and in C-reactive protein, and D-dimer levels.

Citing Articles

Serial Systemic Immune-Inflammation Indices (SSIIi) as Prognostic Markers in Persistent Hypoxic Brain Injury Post-cardiac Arrest: A Case Report.

Wijeratne T, Crewther S, Wijeratne C, Shao R Cureus. 2024; 16(8):e67299.

PMID: 39165618 PMC: 11335377. DOI: 10.7759/cureus.67299.


Secondary headaches - red and green flags and their significance for diagnostics.

Wijeratne T, Wijeratne C, Korajkic N, Bird S, Sales C, Riederer F eNeurologicalSci. 2023; 32:100473.

PMID: 37456555 PMC: 10339125. DOI: 10.1016/j.ensci.2023.100473.


Associations of the neutrophil/lymphocyte ratio, monocyte/ lymphocyte ratio, and platelet/lymphocyte ratio with COVID-19 disease severity in patients with neurological symptoms: A cross-sectional monocentric study.

Sahin B, Celikbilek A, Kocak Y, Koysuren A, Hizmali L J Neurosci Rural Pract. 2023; 14(2):224-229.

PMID: 37181197 PMC: 10174155. DOI: 10.25259/JNRP_6_2022.


Persistent neurological manifestations in long COVID-19 syndrome: A systematic review and meta-analysis.

Pinzon R, Wijaya V, Jody A, Nunsio P, Buana R J Infect Public Health. 2022; 15(8):856-869.

PMID: 35785594 PMC: 9221935. DOI: 10.1016/j.jiph.2022.06.013.


The AIFELL Score as a Predictor of Coronavirus Disease 2019 (COVID-19) Severity and Progression in Hospitalized Patients.

Levenfus I, Ullmann E, Petrowski K, Rose J, Huber L, Stussi-Helbling M Diagnostics (Basel). 2022; 12(3).

PMID: 35328157 PMC: 8947178. DOI: 10.3390/diagnostics12030604.


References
1.
Zhou Y, Li W, Wang D, Mao L, Jin H, Li Y . Clinical time course of COVID-19, its neurological manifestation and some thoughts on its management. Stroke Vasc Neurol. 2020; 5(2):177-179. PMC: 7211099. DOI: 10.1136/svn-2020-000398. View

2.
Yaghi S, Ishida K, Torres J, Mac Grory B, Raz E, Humbert K . SARS-CoV-2 and Stroke in a New York Healthcare System. Stroke. 2020; 51(7):2002-2011. PMC: 7258764. DOI: 10.1161/STROKEAHA.120.030335. View

3.
Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T . Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res. 2020; 191:9-14. PMC: 7177070. DOI: 10.1016/j.thromres.2020.04.024. View

4.
Vingrys A, Healey J, Liew S, Saharinen V, Tran M, Wu W . Validation of a Tablet as a Tangent Perimeter. Transl Vis Sci Technol. 2016; 5(4):3. PMC: 4959816. DOI: 10.1167/tvst.5.4.3. View

5.
Bikdeli B, Madhavan M, Jimenez D, Chuich T, Dreyfus I, Driggin E . COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020; 75(23):2950-2973. PMC: 7164881. DOI: 10.1016/j.jacc.2020.04.031. View