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Cerebral Cavernous Malformation in a Patient with Pontine Hemorrhage: A Case Study

Overview
Journal Clin Pract
Publisher MDPI
Specialty General Medicine
Date 2020 Oct 12
PMID 33042507
Citations 5
Authors
Affiliations
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Abstract

The cerebral cavernous malformations are benign vascular hamartomas, with thin and dilated vascular walls and therefore constantly susceptible to hemorrhage. Clinically, they present with recurrent headaches, acute intracranial hemorrhage and focal neurological deficits. They are considered as and the imaging technique of choice for their diagnosis is magnetic resonance tomography. We present the case of a female patient with acute-onset symptomatology, congruent with a lesion in the basal pons. Her medical history included an intracranial hemorrhage due to a cavernoma, which was surgically removed. The magnetic resonance imaging of the brain revealed two new cavernomas, which were not identified in the imaging conducted in the past. In literature, the cases of de novo appearance of cavernomas are considered highly rare, especially in patients with no consistent family history or medical history of radiation therapy. Resultantly, they should be considered as dynamic lesions, regarding their number, size and behavior.

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References
1.
Rigamonti D, Drayer B, Johnson P, Hadley M, Zabramski J, Spetzler R . The MRI appearance of cavernous malformations (angiomas). J Neurosurg. 1987; 67(4):518-24. DOI: 10.3171/jns.1987.67.4.0518. View

2.
Zabramski J, Wascher T, Spetzler R, Johnson B, Golfinos J, Drayer B . The natural history of familial cavernous malformations: results of an ongoing study. J Neurosurg. 1994; 80(3):422-32. DOI: 10.3171/jns.1994.80.3.0422. View

3.
Agazzi S, Maeder P, Villemure J, Regli L . De novo formation and growth of a sporadic cerebral cavernous malformation: implications for management in an asymptomatic patient. Cerebrovasc Dis. 2003; 16(4):432-5. DOI: 10.1159/000072569. View

4.
Detwiler P, Porter R, Zabramski J, Spetzler R . De novo formation of a central nervous system cavernous malformation: implications for predicting risk of hemorrhage. Case report and review of the literature. J Neurosurg. 1997; 87(4):629-32. DOI: 10.3171/jns.1997.87.4.0629. View

5.
MCCORMICK W, Hardman J, Boulter T . Vascular malformations ("angiomas") of the brain, with special reference to those occurring in the posterior fossa. J Neurosurg. 1968; 28(3):241-51. DOI: 10.3171/jns.1968.28.3.0241. View