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Accounting for Expected Adjusted Effect

Overview
Journal Front Psychol
Date 2020 Oct 12
PMID 33041911
Citations 4
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Abstract

The point that adjustment for confounders do not always guarantee protection against spurious findings and type 1-errors has been made before. The present simulation study indicates that for traditional regression methods, this risk is accentuated by a large sample size, low reliability in the measurement of the confounder, and high reliability in the measurement of the predictor and the outcome. However, this risk might be attenuated by calculating the expected adjusted effect, or the required reliability in the measurement of the possible confounder, with equations presented in the present paper.

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References
1.
Kahneman D . Control of spurious association and the reliability of the controlled variable. Psychol Bull. 1965; 64(5):326-9. DOI: 10.1037/h0022529. View

2.
Fewell Z, Davey Smith G, Sterne J . The impact of residual and unmeasured confounding in epidemiologic studies: a simulation study. Am J Epidemiol. 2007; 166(6):646-55. DOI: 10.1093/aje/kwm165. View

3.
Lee P, Burstyn I . Identification of confounder in epidemiologic data contaminated by measurement error in covariates. BMC Med Res Methodol. 2016; 16:54. PMC: 4870765. DOI: 10.1186/s12874-016-0159-6. View

4.
Westfall J, Yarkoni T . Statistically Controlling for Confounding Constructs Is Harder than You Think. PLoS One. 2016; 11(3):e0152719. PMC: 4816570. DOI: 10.1371/journal.pone.0152719. View

5.
Uchmanowicz I, Gobbens R . The relationship between frailty, anxiety and depression, and health-related quality of life in elderly patients with heart failure. Clin Interv Aging. 2015; 10:1595-600. PMC: 4599570. DOI: 10.2147/CIA.S90077. View