» Articles » PMID: 33037169

Vitamin D Assessment and Precision of Clinical Referrals: Insights Gained from a Teaching Hospital in Southern India

Overview
Journal J Postgrad Med
Specialty General Medicine
Date 2020 Oct 10
PMID 33037169
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: Vitamin D deficiency is widely prevalent worldwide. This has led to a significant surge in referrals for vitamin D assessment in recent years. The cost-effectiveness and rationalization of this practice is uncertain. This study aimed to evaluate the referral pattern for vitamin D testing from a tertiary center in southern India.

Materials And Methods: This was a cross-sectional study done over a period of one year (2017). A total of 95,750 individuals, referred for vitamin D screening were included in this study. Details regarding referring departments and indications for referral were obtained from the computerized hospital information processing system (CHIPS).

Results: The study population exhibited a female preponderance (54.1%) with mean (SD) age of 40.3 (18.5) years. Overall, 44% were found to have vitamin D deficiency. Most of the referrals were from nephrology (15.4%), neurology (10.1%), and orthopedics (9.1%). Nevertheless, dermatology, the staff-clinic, and hematology which contributed to 3.3%, 1.7%, and 1.7% of referrals, had a higher proportion of vitamin D deficiency of 59.1%, 57.7%, and 64.6%, respectively. Although the most common indications for referral were generalized body aches (20.5%) and degenerative bone disorders (20.1%), the proportion of subjects with vitamin D deficiency referred for these indications were 46.1% and 41.6%, respectively. In contrast, chronic steroid use that accounted for 3.3% of the referrals had 59.1% of subjects who were deficient in vitamin D.

Conclusion: To ensure a rational approach to vitamin D testing, clinicians ought to use their discretion to screen those truly at risk for vitamin D deficiency on a case to case basis and avoid indiscriminate testing of the same.

References
1.
Dura-Trave T, Gallinas-Victoriano F, Malumbres-Chacon M, Moreno-Gonzalez P, Aguilera-Albesa S, Yoldi-Petri M . Vitamin D deficiency in children with epilepsy taking valproate and levetiracetam as monotherapy. Epilepsy Res. 2017; 139:80-84. DOI: 10.1016/j.eplepsyres.2017.11.013. View

2.
Ross A, Manson J, Abrams S, Aloia J, Brannon P, Clinton S . The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2010; 96(1):53-8. PMC: 3046611. DOI: 10.1210/jc.2010-2704. View

3.
Jurutka P, Bartik L, Whitfield G, Mathern D, Barthel T, Gurevich M . Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands. J Bone Miner Res. 2008; 22 Suppl 2:V2-10. DOI: 10.1359/jbmr.07s216. View

4.
Holick M . Resurrection of vitamin D deficiency and rickets. J Clin Invest. 2006; 116(8):2062-72. PMC: 1523417. DOI: 10.1172/JCI29449. View

5.
Holick M . Vitamin D deficiency. N Engl J Med. 2007; 357(3):266-81. DOI: 10.1056/NEJMra070553. View