Roles of Biomarkers in Myocardial Fibrosis

Overview

Journal Aging Dis

Specialty Geriatrics

Date 2020 Oct 5

PMID 33014530

Citations 27

Authors

Yuejia Ding

Yuan Wang

Wanqin Zhang

Qiujin Jia

Xiaoling Wang

Yanyang Li

Shichao Lv

Junping Zhang

Affiliations

Soon will be listed here.

Abstract

Myocardial fibrosis is observed in various cardiovascular diseases and plays a key role in the impairment of cardiac function. Endomyocardial biopsy, as the gold standard for the diagnosis of myocardial fibrosis, has limitations in terms of clinical application. Therefore, biomarkers have been recommended for noninvasive assessment of myocardial fibrosis. This review discusses the role of biomarkers in myocardial fibrosis from the perspective of collagen.

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References

He Q, Wang F, Honda T, James J, Li J, Redington A . Loss of miR-144 signaling interrupts extracellular matrix remodeling after myocardial infarction leading to worsened cardiac function. Sci Rep. 2018; 8(1):16886. PMC: 6237773. DOI: 10.1038/s41598-018-35314-6. View

Takawale A, Zhang P, Patel V, Wang X, Oudit G, Kassiri Z . Tissue Inhibitor of Matrix Metalloproteinase-1 Promotes Myocardial Fibrosis by Mediating CD63-Integrin β1 Interaction. Hypertension. 2017; 69(6):1092-1103. DOI: 10.1161/HYPERTENSIONAHA.117.09045. View

Dehne N, Kerkweg U, Flohe S, Brune B, Fandrey J . Activation of hypoxia-inducible factor 1 in skeletal muscle cells after exposure to damaged muscle cell debris. Shock. 2011; 35(6):632-8. DOI: 10.1097/SHK.0b013e3182111f3d. View

Dong N, Chen S, Yang J, He L, Liu P, Zheng D . Plasma soluble corin in patients with heart failure. Circ Heart Fail. 2010; 3(2):207-11. PMC: 2879139. DOI: 10.1161/CIRCHEARTFAILURE.109.903849. View

Manhenke C, Orn S, Squire I, Radauceanu A, Alla F, Zannad F . The prognostic value of circulating markers of collagen turnover after acute myocardial infarction. Int J Cardiol. 2010; 150(3):277-82. DOI: 10.1016/j.ijcard.2010.04.034. View

Voloshenyuk T, Landesman E, Khoutorova E, Hart A, Gardner J . Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling. Cytokine. 2011; 55(1):90-7. DOI: 10.1016/j.cyto.2011.03.024. View

Dean R, Balding L, Candido R, Burns W, Cao Z, Twigg S . Connective tissue growth factor and cardiac fibrosis after myocardial infarction. J Histochem Cytochem. 2005; 53(10):1245-56. DOI: 10.1369/jhc.4A6560.2005. View

Wei Y, Wu Y, Feng K, Zhao Y, Tao R, Xu H . Astragaloside IV inhibits cardiac fibrosis via miR-135a-TRPM7-TGF-β/Smads pathway. J Ethnopharmacol. 2019; 249:112404. DOI: 10.1016/j.jep.2019.112404. View

Heid J, Cencioni C, Ripa R, Baumgart M, Atlante S, Milano G . Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health. Sci Rep. 2017; 7(1):16839. PMC: 5715159. DOI: 10.1038/s41598-017-16829-w. View

10.

Yan W, Wu F, Morser J, Wu Q . Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme. Proc Natl Acad Sci U S A. 2000; 97(15):8525-9. PMC: 26981. DOI: 10.1073/pnas.150149097. View

11.

Colige A, Vandenberghe I, Thiry M, Lambert C, Van Beeumen J, Li S . Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3. J Biol Chem. 2001; 277(8):5756-66. DOI: 10.1074/jbc.M105601200. View

12.

Engvall E, Hessle H, Klier G . Molecular assembly, secretion, and matrix deposition of type VI collagen. J Cell Biol. 1986; 102(3):703-10. PMC: 2114116. DOI: 10.1083/jcb.102.3.703. View

13.

Hasty K, Jeffrey J, Hibbs M, Welgus H . The collagen substrate specificity of human neutrophil collagenase. J Biol Chem. 1987; 262(21):10048-52. View

14.

Hong L, Lai H, Fang Y, Tao Y, Qiu Y . Silencing CTGF/CCN2 inactivates the MAPK signaling pathway to alleviate myocardial fibrosis and left ventricular hypertrophy in rats with dilated cardiomyopathy. J Cell Biochem. 2018; 119(11):9519-9531. DOI: 10.1002/jcb.27268. View

15.

Xue K, Zhang J, Li C, Li J, Wang C, Zhang Q . The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis. J Cell Mol Med. 2019; 23(6):4229-4243. PMC: 6533491. DOI: 10.1111/jcmm.14313. View

16.

Lindsay M, Maxwell P, Dunn F . TIMP-1: a marker of left ventricular diastolic dysfunction and fibrosis in hypertension. Hypertension. 2002; 40(2):136-41. DOI: 10.1161/01.hyp.0000024573.17293.23. View

17.

Bujak M, Frangogiannis N . The role of TGF-beta signaling in myocardial infarction and cardiac remodeling. Cardiovasc Res. 2006; 74(2):184-95. PMC: 1924687. DOI: 10.1016/j.cardiores.2006.10.002. View

18.

Das A, Ganesh K, Khanna S, Sen C, Roy S . Engulfment of apoptotic cells by macrophages: a role of microRNA-21 in the resolution of wound inflammation. J Immunol. 2014; 192(3):1120-9. PMC: 4358325. DOI: 10.4049/jimmunol.1300613. View

19.

Zile M, OMeara E, Claggett B, Prescott M, Solomon S, Swedberg K . Effects of Sacubitril/Valsartan on Biomarkers of Extracellular Matrix Regulation in Patients With HFrEF. J Am Coll Cardiol. 2019; 73(7):795-806. DOI: 10.1016/j.jacc.2018.11.042. View

20.

Lin Y, Lin Y, Wu X, Ko C, Yen R, Chen Y . The relationship between serum fibrosis markers and restrictive ventricular filling in patients with heart failure with reduced ejection fraction: A technetium-99m radionuclide ventriculography study. Oncotarget. 2016; 8(2):2381-2390. PMC: 5356808. DOI: 10.18632/oncotarget.13795. View