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Potential Effect of Intravenous Immunoglobulin Against Paraneoplastic Cerebellar Degeneration in Progressive Ovarian Cancer

Overview
Journal Gynecol Oncol Rep
Publisher Elsevier
Date 2020 Oct 2
PMID 33005721
Citations 3
Authors
Takashi Shibata
Tetsuya Oishi
Yasunori Fukuoka
Shigeki Nishikawa
Noriaki Iizuka
Hiroki Kato
Affiliations
Soon will be listed here.
Abstract

We report the effect of intravenous immunoglobulin (IVIG) against paraneoplastic cerebellar degeneration (PCD) in a case of progressive ovarian cancer. Our patient developed PCD soon after postoperative chemotherapy and became bedridden. After undergoing IVIG, however, symptoms dramatically improved, and unexpectedly the remaining tumors were confirmed to have completely disappeared. When PCD is diagnosed, IVIG treatment should be attempted to reduce neuropathy regardless of its degree and the state of the cancer. It may also have further potential benefits that should be considered.

Citing Articles

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Giucca A, Morrison H, Wilson T, Cossburn M BMJ Case Rep. 2023; 16(5).

PMID: 37137547 PMC: 10163414. DOI: 10.1136/bcr-2022-251277.

An Etiological Investigation of Paraneoplastic Cerebellar Degeneration in Ovarian Cancer Patients: A Systematic Review.

Fidahussain A, Abid A, Paracha A, Jeevan V, Rueve J, Engelhardt M Cureus. 2022; 14(11):e31154.

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Update on Paraneoplastic Cerebellar Degeneration.

Loehrer P, Zieger L, Simon O Brain Sci. 2021; 11(11).

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