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Magnetic Resonance Imaging of Recurrent Adult Granulosa Cell Tumor of the Ovary: A Retrospective Analysis of 11 Cases

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Specialty Radiology
Date 2020 Sep 25
PMID 32976259
Citations 3
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Abstract

Objective: The aim of the study was to characterize magnetic resonance imaging findings in patients with recurrent ovarian adult granulosa cell tumors (AGCTs).

Methods: Clinical and magnetic resonance imaging manifestations of recurrent AGCTs were evaluated in 11 patients.

Results: Initial recurrences of AGCT were diagnosed between 13 months and 30 years (mean, 11.3 years). Recurrent tumors were located in the pelvic peritoneum, the abdominal peritoneum, the retroperitoneum, and bone. The number of recurrent tumors varied from 1 to 5. Tumors varied in morphology and all margins were well circumscribed. The internal structures noted were as follows: multilocular cystic and solid and cystic. Furthermore, internal hemorrhage and sponge-like multicystic components were identified.

Conclusions: Ovarian AGCTs recurred in the pelvic peritoneum, abdominal peritoneum, and the retroperitoneal lymph nodes. Large recurrent AGCTs were commonly well circumscribed, round or lobulated, and multilocular cystic or solid and cystic. Moreover, they frequently included internal hemorrhage and sponge-like multicystic components.

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References
1.
Bergamini A, Cormio G, Ferrandina G, Lorusso D, Giorda G, Scarfone G . Conservative surgery in stage I adult type granulosa cells tumors of the ovary: Results from the MITO-9 study. Gynecol Oncol. 2019; 154(2):323-327. DOI: 10.1016/j.ygyno.2019.05.029. View

2.
Petraglia F, Luisi S, Pautier P, Sabourin J, Rey R, Lhomme C . Inhibin B is the major form of inhibin/activin family secreted by granulosa cell tumors. J Clin Endocrinol Metab. 1998; 83(3):1029-32. DOI: 10.1210/jcem.83.3.4800. View

3.
Horta M, Cunha T . Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists. Diagn Interv Radiol. 2015; 21(4):277-86. PMC: 4498422. DOI: 10.5152/dir.2015.34414. View

4.
Fox H, Agrawal K, Langley F . A clinicopathologic study of 92 cases of granulosa cell tumor of the ovary with special reference to the factors influencing prognosis. Cancer. 1975; 35(1):231-41. DOI: 10.1002/1097-0142(197501)35:1<231::aid-cncr2820350128>3.0.co;2-o. View

5.
Young R . Ovarian Sex Cord-Stromal Tumors: Reflections on a 40-Year Experience With a Fascinating Group of Tumors, Including Comments on the Seminal Observations of Robert E. Scully, MD. Arch Pathol Lab Med. 2018; 142(12):1459-1484. DOI: 10.5858/arpa.2018-0291-RA. View