A Call to Action to Evaluate Renal Functional Reserve in Patients with COVID-19

Overview

Journal Am J Physiol Renal Physiol

Publisher American Physiological Society

Specialties Nephrology
Physiology

Date 2020 Sep 24

PMID 32969711

Citations 7

Authors

Vincenzo Cantaluppi

Gabriele Guglielmetti

Sergio Dellepiane

Marita Marengo

Ravindra L Mehta

Claudio Ronco

Affiliations

Soon will be listed here.

Abstract

Coronavirus disease 2019 (COVID-19) poses an unprecedented challenge to world health systems, substantially increasing hospitalization and mortality rates in all affected countries. Being primarily a respiratory disease, COVID-19 is mainly associated with pneumonia or minor upper respiratory tract symptoms; however, different organs can sustain considerable (if not terminal) damage because of coronavirus. Acute kidney injury is the most common complication of COVID-19-related pneumonia, and more than 20% of patients requiring ventilatory support develop renal failure. Additionally, chronic kidney disease is a major risk factor for COVID-19 severity and mortality. All these data demonstrate the relevance of renal function assessment in patients with COVID-19 and the need of early kidney-directed diagnostic and therapeutic approaches. However, the sole assessment of renal function could be not entirely indicative of kidney tissue status. In this viewpoint, we discuss the clinical significance and potential relevance of renal functional reserve evaluation in patients with COVID-19.

Citing Articles

Potential utility of renal functional reserve testing in clinical nephrology.

Mueller T, Luyckx V Curr Opin Nephrol Hypertens. 2023; 33(1):130-135.

PMID: 37706475 PMC: 10715690. DOI: 10.1097/MNH.0000000000000930.

Acute Kidney Injury and Blood Purification Techniques in Severe COVID-19 Patients.

Napoli M, Provenzano M, Hu L, Bini C, Abenavoli C, La Manna G J Clin Med. 2022; 11(21).

PMID: 36362514 PMC: 9658337. DOI: 10.3390/jcm11216286.

Comparison of Two Waves of COVID-19 in Critically Ill Patients: A Retrospective Observational Study.

Jana K, Yap E, Janga K, Greenberg S Int J Nephrol. 2022; 2022:3773625.

PMID: 35665075 PMC: 9161135. DOI: 10.1155/2022/3773625.

Management of Acute Kidney Injury and Extracorporeal Blood Purification Therapies During the COVID-19 Pandemic: The Italian SIN-SIAARTI Joint Survey (and Recommendations for Clinical Practice).

De Rosa S, Marengo M, Romagnoli S, Fiorentino M, Fanelli V, Fiaccadori E Front Med (Lausanne). 2022; 9:850535.

PMID: 35463000 PMC: 9021595. DOI: 10.3389/fmed.2022.850535.

Protein requirements for critically ill ventilator-dependent patients with COVID-19.

Buckley C, Prasanna N, Mays A, Tinsley J, Dickerson R Nutr Clin Pract. 2021; 36(5):984-992.

PMID: 34468046 PMC: 8662189. DOI: 10.1002/ncp.10763.

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