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Carotid Plaque Imaging and the Risk of Atherosclerotic Cardiovascular Disease

Overview
Journal Cardiovasc Diagn Ther
Publisher AME Publishing Company
Specialty Cardiology & Vascular Diseases
Date 2020 Sep 24
PMID 32968660
Citations 21
Authors
Guangming Zhu
Jason Hom
Ying Li
Bin Jiang
Fatima Rodriguez
Dominik Fleischmann
David Saloner
Michele Porcu
Yanrong Zhang
Luca Saba
Max Wintermark
Affiliations
Soon will be listed here.
Abstract

Carotid artery plaque is a measure of atherosclerosis and is associated with future risk of atherosclerotic cardiovascular disease (ASCVD), which encompasses coronary, cerebrovascular, and peripheral arterial diseases. With advanced imaging techniques, computerized tomography (CT) and magnetic resonance imaging (MRI) have shown their potential superiority to routine ultrasound to detect features of carotid plaque vulnerability, such as intraplaque hemorrhage (IPH), lipid-rich necrotic core (LRNC), fibrous cap (FC), and calcification. The correlation between imaging features and histological changes of carotid plaques has been investigated. Imaging of carotid features has been used to predict the risk of cardiovascular events. Other techniques such as nuclear imaging and intra-vascular ultrasound (IVUS) have also been proposed to better understand the vulnerable carotid plaque features. In this article, we review the studies of imaging specific carotid plaque components and their correlation with risk scores.

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