Transbronchial Cryobiopsy for Miliary Tuberculosis Mimicking Hypersensitivity Pneumonitis

Overview

Journal Intern Med

Specialty General Medicine

Date 2020 Sep 23

PMID 32963150

Citations 1

Authors

Shingo Nasu

Kunimitsu Kawahara

Yuki Han

Norio Okamoto

Yoshitaka Tamura

Hidekazu Suzuki

Takayuki Shiroyama

Yumiko Samejima

Tomohiro Kanai

Yoshimi Noda

Ayako Tanaka

Naoko Morishita

Kayo Ueda

Shoji Hashimoto

Tomonori Hirashima

Takayuki Nagai

Affiliations

Soon will be listed here.

Abstract

Miliary tuberculosis is a potentially lethal type of tuberculosis that results from the hematogenous dissemination of Mycobacterium tuberculosis bacilli. We herein describe the case of a 34-year-old man that presented with a one-month history of cough and fever, while his sputum smear results were negative. Chest computed tomography revealed bilateral centrilobular ground-glass opacification (GGO), suggestive of hypersensitivity pneumonitis; thus, bronchoscopy was performed. Cryobiopsy specimens revealed necrotic granulomas. A re-examination of sputum after bronchoscopy identified Mycobacterium tuberculosis, and miliary tuberculosis was diagnosed. A cryobiopsy might be useful for diagnosing miliary tuberculosis pathologically, particularly when miliary nodules may be masked by GGO.

Citing Articles

Transbronchial Cryobiopsy for the Diagnosis of Culture Negative Miliary Tuberculosis.

Siddiqui A Clin Case Rep. 2024; 12(11):e9595.

PMID: 39568530 PMC: 11576326. DOI: 10.1002/ccr3.9595.

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