Development of Coinage Metal Nanoclusters As Antimicrobials to Combat Bacterial Infections

Overview

Journal J Mater Chem B

Publisher Royal Society of Chemistry

Specialty Biomedical Engineering

Date 2020 Sep 21

PMID 32955539

Citations 5

Authors

Dan Li

Beena Kumari

Jessa Marie Makabenta

Bailong Tao

Kun Qian

Xifan Mei

Vincent M Rotello

Affiliations

Soon will be listed here.

Abstract

Infections from antibiotic-resistant bacteria have caused huge economic loss and numerous deaths over the past decades. Researchers are exploring multiple strategies to combat these bacterial infections. Metal nanomaterials have been explored as therapeutics against these infections owing to their relatively low toxicity, broad-spectrum activity, and low bacterial resistance development. Some coinage metal nanoclusters, such as gold, silver, and copper nanoclusters, can be readily synthesized. These nanoclusters can feature multiple useful properties, including ultra-small size, high catalytic activity, unique photoluminescent properties, and photothermal effect. Coinage metal nanoclusters have been investigated as antimicrobials, but more research is required to tap their full potential. In this review, we discuss multiple advantages and the prospect of using gold/silver/copper nanoclusters as antimicrobials.

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