» Articles » PMID: 32948151

Intravertebral Cleft in Pathological Vertebral Fracture Resulting from Spinal Tuberculosis: a Case Report and Literature Review

Overview
Publisher Biomed Central
Specialties Orthopedics
Physiology
Date 2020 Sep 19
PMID 32948151
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Among common findings in osteoporotic vertebral compression fractures (OVCFs), the intravertebral cleft (IVC) is usually considered a benign lesion. The current study was aimed to present a rare case of vertebral fracture caused by IVC-related spinal tuberculosis.

Case Presentation: A 73-year-old female complained of back pain and weakness in lower limbs for 2 weeks. 3 months ago, after a minor trauma, she got back pain without weakness in lower limbs. Initially, she was diagnosed with a L1 compression fracture and accepted conservative treatment. After an asymptomatic period, she complained progressive pain at the fracture position with weakness of both lower limbs and was referred to our hospital with suspicion of Kümmell's disease. The patient underwent posterior debridement and internal fixation for decompression and stabilization of the spine. Pathological examinations revealed the patient with spinal tuberculosis.

Conclusions: Although IVC is common in patients with OCVFs, there are some cases believed to be found in patients with spinal tuberculosis or infection. Further test, like CT-guided puncture biopsy, may be required before decisive treatment when an IVC is observed.

Citing Articles

Tuberculous Spondylitis and Paravertebral Abscess Formation Following Vertebroplasty: A Case Report and Review of the Literature.

Pi W, Liu Y, Chen H, Zhao H Infect Drug Resist. 2024; 17:5171-5178.

PMID: 39605988 PMC: 11600914. DOI: 10.2147/IDR.S496726.


Effects of Percutaneous Kyphoplasty for the Treatment of Thoracic Osteoporotic Vertebral Compression Fractures with or without Intravertebral Cleft in Elderly Patients.

He W, Zhou Q, Lv J, Shen Y, Liu H, Yang H Int J Gen Med. 2024; 17:193-203.

PMID: 38268860 PMC: 10807278. DOI: 10.2147/IJGM.S447623.


Osteoimmunology: The effect of autoimmunity on fracture healing and skeletal analysis.

Loncar S, Halcrow S, Swales D Forensic Sci Int Synerg. 2023; 6:100326.

PMID: 37091290 PMC: 10120377. DOI: 10.1016/j.fsisyn.2023.100326.

References
1.
Libicher M, Appelt A, Berger I, Baier M, Meeder P, Grafe I . The intravertebral vacuum phenomen as specific sign of osteonecrosis in vertebral compression fractures: results from a radiological and histological study. Eur Radiol. 2007; 17(9):2248-52. DOI: 10.1007/s00330-007-0684-0. View

2.
McDonald R, Trout A, Gray L, Dispenzieri A, Thielen K, Kallmes D . Vertebroplasty in multiple myeloma: outcomes in a large patient series. AJNR Am J Neuroradiol. 2008; 29(4):642-8. PMC: 7978179. DOI: 10.3174/ajnr.A0918. View

3.
Wei H, Dong C, Zhu Y . Posterior Fixation Combined with Vertebroplasty or Vertebral Column Resection for the Treatment of Osteoporotic Vertebral Compression Fractures with Intravertebral Cleft Complicated by Neurological Deficits. Biomed Res Int. 2020; 2019:4126818. PMC: 6931022. DOI: 10.1155/2019/4126818. View

4.
Sarli M, Perez Manghi F, Gallo R, Zanchetta J . The vacuum cleft sign: an uncommon radiological sign. Osteoporos Int. 2005; 16(10):1210-4. DOI: 10.1007/s00198-005-1833-4. View

5.
Girolami M, Boriani S, Bandiera S, Barbanti-Brodano G, Ghermandi R, Terzi S . Biomimetic 3D-printed custom-made prosthesis for anterior column reconstruction in the thoracolumbar spine: a tailored option following en bloc resection for spinal tumors : Preliminary results on a case-series of 13 patients. Eur Spine J. 2018; 27(12):3073-3083. DOI: 10.1007/s00586-018-5708-8. View