» Articles » PMID: 32928125

The Clinical Significance of the Incorporation of Tissue Doppler Imaging into Low-dose Dobutamine Stress Echocardiography in Patients with Aortic Stenosis Prior to Transcatheter Aortic Valve Implantation

Overview
Publisher Biomed Central
Date 2020 Sep 15
PMID 32928125
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Low-dose dobutamine stress echocardiography (DSE) is indicated in patients with low flow (stroke volume index [SVi] < 35 ml/m) low gradient (mean pressure gradient < 40 mmHg) and left ventricular ejection fraction (LVEF) < 50% aortic stenosis (AS) to assess LV contractile reserve (> 20% increase in SVi) and severity grade of AS. Severe AS is defined by a mean pressure gradient of 40 mmHg occurring at any time during the test when aortic valve area remains < 1.0 cm.

Case Presentation: This case report highlights the utility of mitral annular systolic velocity (S') by tissue Doppler imaging and peak LV outflow tract (LVOT) velocity as markers of LV intrinsic contractile function during DSE in a patient with low flow low gradient AS and reduced EF prior to transcatheter aortic valve implantation (TAVI).

Conclusions: Mitral annular S' and peak LVOT velocities are reliable markers of LV intrinsic contractile function and should be incorporated into routine low-dose DSE.

References
1.
Strange G, Stewart S, Celermajer D, Prior D, Scalia G, Marwick T . Poor Long-Term Survival in Patients With Moderate Aortic Stenosis. J Am Coll Cardiol. 2019; 74(15):1851-1863. DOI: 10.1016/j.jacc.2019.08.004. View

2.
Levy F, Laurent M, Monin J, Maillet J, Pasquet A, Le Tourneau T . Aortic valve replacement for low-flow/low-gradient aortic stenosis operative risk stratification and long-term outcome: a European multicenter study. J Am Coll Cardiol. 2008; 51(15):1466-72. DOI: 10.1016/j.jacc.2007.10.067. View

3.
Lindqvist P, Bajraktari G, Molle R, Palmerini E, Holmgren A, Mondillo S . Valve replacement for aortic stenosis normalizes subendocardial function in patients with normal ejection fraction. Eur J Echocardiogr. 2010; 11(7):608-13. DOI: 10.1093/ejechocard/jeq026. View

4.
Baumgartner H, Hung J, Bermejo J, Chambers J, Edvardsen T, Goldstein S . Recommendations on the Echocardiographic Assessment of Aortic Valve Stenosis: A Focused Update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. J Am Soc Echocardiogr. 2017; 30(4):372-392. DOI: 10.1016/j.echo.2017.02.009. View

5.
Chambers J, Rajani R, Parkin D, Saeed S . Rapid early rise in heart rate on treadmill exercise in patients with asymptomatic moderate or severe aortic stenosis: a new prognostic marker?. Open Heart. 2019; 6(1):e000950. PMC: 6361371. DOI: 10.1136/openhrt-2018-000950. View