Exploring Emotional Distress, Psychological Traits and Attitudes in Patients with Chronic Migraine Undergoing OnabotulinumtoxinA Prophylaxis Versus Withdrawal Treatment

Overview

Journal Toxins (Basel)

Publisher MDPI

Specialty Toxicology

Date 2020 Sep 11

PMID 32911799

Citations 12

Authors

Valeria Donisi

Maria Angela Mazzi

Marialuisa Gandolfi

Giuseppe Deledda

Fabio Marchioretto

Simone Battista

Sara Poli

Matteo Giansante

Eleonora Geccherle

Cinzia Perlini

Nicola Smania

Lidia Del Piccolo

Affiliations

Soon will be listed here.

Abstract

This explorative cross-sectional study aims at exploring emotional distress, psychological profiles, and the attitude towards receiving psychological support in eighty-seven patients with chronic migraine (CM) undergoing OnabotulinumtoxinA prophylactic treatment (OBT-A, n = 40) or withdrawal treatment (WT, n = 47). The outcomes were explored through a specific battery of questionnaires. 25% of patients undergoing OBT-A and almost half of the patients undergoing WT reported psychological distress of at least moderate-severe level, respectively. Coping strategies, self-efficacy, and perceived social support were similar in the two groups. Patients undergoing OBT-A presented lower psychological inflexibility than patients undergoing WT. Predictors of higher psychological distress were low perceived social support by friends, low self-efficacy, and higher avoidance strategies. In both groups, most of the patients evaluated receiving psychological support to be useful (79%). The potential beneficial effects of OBT-A on the severity of symptoms and psychological distress might further support its role in the multidisciplinary management of patients with CM. Identifying patients with psychological vulnerabilities who may benefit from psychological support is relevant in patients with CM.

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