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Response to "letter Concerning: Clewell (2019) Incorporation of Metabolism Data and Physiologically Based Pharmacokinetic Modeling in a Risk Assessment for Chloroprene." (UIHT-2020-0053)

Overview
Journal Inhal Toxicol
Publisher Informa Healthcare
Specialty Toxicology
Date 2020 Sep 9
PMID 32900235
Citations 1
Authors
H J Clewell 3rd
J L Campbell
C Van Landingham
A Franzen
M Yoon
D E Dodd
M E Andersen
P R Gentry
Affiliations
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Citing Articles

Using available metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.

Campbell Jr J, Clewell 3rd H, Van Landingham C, Gentry P, Andersen M Front Pharmacol. 2023; 14:1223808.

PMID: 37663267 PMC: 10472072. DOI: 10.3389/fphar.2023.1223808.