A Review of the Potential Interaction of Selenium and Iodine on Placental and Child Health

Overview

Journal Nutrients

Date 2020 Sep 5

PMID 32887377

Citations 11

Authors

Nahal Habibi

Jessica A Grieger

Tina Bianco-Miotto

Affiliations

Soon will be listed here.

Abstract

A healthy pregnancy is important for the growth and development of a baby. An adverse pregnancy outcome is associated with increased chronic disease risk for the mother and offspring. An optimal diet both before and during pregnancy is essential to support the health of the mother and offspring. A key mediator of the effect of maternal nutrition factors on pregnancy outcomes is the placenta. Complicated pregnancies are characterized by increased oxidative stress in the placenta. Selenium and iodine are micronutrients that are involved in oxidative stress in placental cells. To date, there has been no comprehensive review investigating the potential synergistic effect of iodine and selenium in the placenta and how maternal deficiencies may be associated with increased oxidative stress and hence adverse pregnancy outcomes. We undertook a hypothesis-generating review on selenium and iodine, to look at how they may relate to pregnancy complications through oxidative stress. We propose how they may work together to impact pregnancy and placental health and explore how deficiencies in these micronutrients during pregnancy may impact the future health of offspring.

Citing Articles

Association Between Dietary Phytochemical Index and Neonatal Thyroid Function.

Hashemi Dehkordi V, Khoshhali M, Heidari-Beni M, Hashemi Dehkordi E, Hashemipour M, Mostofizadeh N J Pregnancy. 2024; 2024:9558023.

PMID: 38919582 PMC: 11199066. DOI: 10.1155/2024/9558023.

Effects of Gestational Diabetes Mellitus and Selenium Deficiency on the Offspring Growth and Blood Glucose Mechanisms of C57BL/6J Mice.

Xu W, Gong J, Chen Y, Chen Y, Chen S, Wu Y Nutrients. 2023; 15(21).

PMID: 37960172 PMC: 10647445. DOI: 10.3390/nu15214519.

Selenium status in term neonates, according to birth weight and gestational age, in relation to maternal hypertensive pathology.

Bizerea-Moga T, Pitulice L, Bizerea-Spiridon O, Angelescu C, Marginean O, Moga T Front Pediatr. 2023; 11:1157689.

PMID: 37063670 PMC: 10101720. DOI: 10.3389/fped.2023.1157689.

Effect of Lipid-Based Multiple Micronutrients Supplementation in Underweight Primigravida Pre-Eclamptic Women on Maternal and Pregnancy Outcomes: Randomized Clinical Trial.

Sher N, Mubaraki M, Zafar H, Nazli R, Zafar M, Fatima S Medicina (Kaunas). 2022; 58(12).

PMID: 36556974 PMC: 9783323. DOI: 10.3390/medicina58121772.

Iodine nutrition level and thyroid function in pregnant women in the Yongchuan district of Chongqing.

Liu X, Xiao Z, Cheng L, Jian L J Clin Transl Res. 2022; 8(6):516-522.

PMID: 36452005 PMC: 9706315.

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