Refractive Stability of a New Single-piece Hydrophobic Acrylic Intraocular Lens and Corneal Wound Repair After Implantation Using a New Automated Intraocular Lens Delivery System

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2020 Sep 3

PMID 32877454

Citations 8

Authors

Kazuno Negishi

Sachiko Masui

Hidemasa Torii

Yasuyo Nishi

Kazuo Tsubota

Affiliations

Soon will be listed here.

Abstract

Purpose: To investigate refractive stability and characterize corneal incision repair up to 3 months after implantation of a new hydrophobic acrylic intraocular lens (IOL) with hydroxyethylmethacrylate using a new automated IOL delivery system.

Methods: This prospective case series included 50 eyes of 50 patients undergoing phacoemulsification and implantation of the Clareon® CNA0T0 IOL using the AutonoMe® automated delivery system in the Department of Ophthalmology, Keio University School of Medicine. The clinical data were collected from 46 eyes of 46 patients preoperatively and 1 day, 1 week, and 1 and 3 months postoperatively. Endothelial-side incision gaping, posterior incision retraction, and Descemet's membrane detachment were recorded as present or absent using anterior-segment optical coherence tomography postoperatively.

Results: The uncorrected distance and corrected distance visual acuities improved and stabilized 1 week postoperatively. The anterior chamber depth was stable from 1 week postoperatively. The subjective refraction was stable from 1 day postoperatively. Descemet's membrane detachments and endothelial-side wound gaping were seen in 19 (41.3%) eyes and 34 (73.9%) eyes 1 day postoperatively and decreased gradually. Posterior incision retraction was seen in eight eyes (17.4%) on day 1 and increased to 19 eyes (41.3%) 3 months postoperatively.

Conclusions: The Clareon IOL had excellent refractive stability from day 1 postoperatively. The AutonoMe automated delivery system enables safe IOL implantation through a 2.4-mm corneal incision, although the wound required longer than 1 month to heal postoperatively.

Citing Articles

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Christenbury J, Hall B Clin Ophthalmol. 2024; 18:3485-3491.

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Clinical Evaluation of a Hydrophobic Intraocular Lens Using a Preloaded Automated Injector in a Korean Population.

Kim H, Seo K, Yoon K, Choi C, Chung T, Hyon J Clin Ophthalmol. 2023; 17:3353-3363.

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Evaluation of Visual Outcomes and 3-Month Refractive Stability of a New Hydrophobic Acrylic Intraocular Lens.

Blehm C, Hall B Clin Ophthalmol. 2023; 17:1859-1864.

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Titiyal J, Basak S, Shetty N, Mathur U, Padmanabhan P, Ganesh S Clin Ophthalmol. 2022; 16:4215-4225.

PMID: 36561374 PMC: 9767064. DOI: 10.2147/OPTH.S379054.

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