REPRODUCIBILITY OF PHYSIOLOGICAL VARIABLES OF THE SIX-MINUTE WALK TEST IN HEALTHY STUDENTS

Overview

Journal Rev Paul Pediatr

Specialty Pediatrics

Date 2020 Sep 3

PMID 32876306

Authors

Patricia Morgana Rentz Keil

Janaina Cristina Scalco

Renata Maba Goncalves Wamosy

Camila Isabel Santos Schivinski

Affiliations

Soon will be listed here.

Abstract

Objective: To verify the reproducibility of the six-minute walk test (6MWT) performance and its physiological variables in healthy students.

Methods: This is as prospective cross-sectional study. The sample consisted of healthy students aged 6-12 years old from public and private schools in the region of Florianópolis City, Santa Catarina State, (Southern Brazil). The medical state was considered according to the health records and scores on the International Study of Asthma and Allergies in Childhood (ISAAC) and the spirometric values of forced expiratory volume in the first second and forced vital capacity above 80% of what was predicted. Two 6MWTs were conducted with a 30-minute interval between them, following the recommendations from the American Thoracic Society. Physiologic variables were recorded using the portable telemetric gas analyzer K4b2 (Cosmed®, Italy). For analysis, the dyspnea index, the perception of effort and performance variables identified in both 6MWT were considered. Data distribution was verified with the Shapiro-Wilk test and statistical analysis included paired t-test or Wilcoxon test, and intraclass correlation coefficient (ICC). The significance level adopted was 5%.

Results: A total of 22 students with a mean age of 10.2±1.5 years participated in the study. The covered distance and the variation of oxygen consumption reproducibility between the two 6MWTs presented ICC=0.76 and ICC=0.86, respectively. There was also similar behavior of the physiological variables when comparing the two tests (p=0.001), especially the minute volume (MV), the oxygen consumption (VO2), and the carbon dioxide production (VCO2).

Conclusions: The 6MWT showed reproducible values, both in performance and physiological parameters, in the healthy students analyzed.

References

Pereira F, Goncalves de Oliveira Ribeiro M, Ribeiro A, Toro A, Hessel G, Ribeiro J . Functional performance on the six-minute walk test in patients with cystic fibrosis. J Bras Pneumol. 2012; 37(6):735-44. DOI: 10.1590/s1806-37132011000600006. View

Cunha M, Rozov T, de Oliveira R, Jardim J . Six-minute walk test in children and adolescents with cystic fibrosis. Pediatr Pulmonol. 2006; 41(7):618-22. DOI: 10.1002/ppul.20308. View

Polgar G, Weng T . The functional development of the respiratory system from the period of gestation to adulthood. Am Rev Respir Dis. 1979; 120(3):625-95. DOI: 10.1164/arrd.1979.120.3.625. View

de Assis Pereira Cacau L, Santana-Filho V, Maynard L, Gomes Neto M, Fernandes M, Carvalho V . Reference Values for the Six-Minute Walk Test in Healthy Children and Adolescents: a Systematic Review. Braz J Cardiovasc Surg. 2016; 31(5):381-388. PMC: 5144571. DOI: 10.5935/1678-9741.20160081. View

Sanabria D, Luque-Casado A, Perales J, Ballester R, Ciria L, Huertas F . The relationship between vigilance capacity and physical exercise: a mixed-effects multistudy analysis. PeerJ. 2019; 7:e7118. PMC: 6556370. DOI: 10.7717/peerj.7118. View

Bos G, Lelieveld O, Scheenstra R, Sauer P, Geertzen J, Dijkstra P . Physical activity and aerobic fitness in children after liver transplantation. Pediatr Transplant. 2019; 23(5):e13465. DOI: 10.1111/petr.13465. View

Maggio A, Vuistiner P, Crettenand A, Tabin R, Martin X, Beghetti M . Adapting the "Chester step test" to predict peak oxygen uptake in children. Swiss Med Wkly. 2017; 147:w14435. DOI: 10.4414/smw.2017.14435. View

KNUDSON R, Slatin R, LEBOWITZ M, Burrows B . The maximal expiratory flow-volume curve. Normal standards, variability, and effects of age. Am Rev Respir Dis. 1976; 113(5):587-600. DOI: 10.1164/arrd.1976.113.5.587. View

Donadio M, Heinzmann-Filho J, Vendrusculo F, Frasson P, Marostica P . Six-Minute Walk Test Results Predict Risk of Hospitalization for Youths with Cystic Fibrosis: A 5-Year Follow-Up Study. J Pediatr. 2017; 182:204-209.e1. DOI: 10.1016/j.jpeds.2016.11.071. View

10.

Bohannon R, Bubela D, Wang Y, Magasi S, Gershon R . Six-Minute Walk Test Vs. Three-Minute Step Test for Measuring Functional Endurance. J Strength Cond Res. 2013; 29(11):3240-4. PMC: 4004706. DOI: 10.1519/JSC.0000000000000253. View

11.

Holland A, Spruit M, Troosters T, Puhan M, Pepin V, Saey D . An official European Respiratory Society/American Thoracic Society technical standard: field walking tests in chronic respiratory disease. Eur Respir J. 2014; 44(6):1428-46. DOI: 10.1183/09031936.00150314. View

12.

Morales Mestre N, Audag N, Caty G, Reychler G . Learning and Encouragement Effects on Six-Minute Walking Test in Children. J Pediatr. 2018; 198:98-103. DOI: 10.1016/j.jpeds.2018.02.073. View

13.

Ghorayeb N, Stein R, Daher D, da Silveira A, Eduardo Fonteles Ritt L, Santos D . The Brazilian Society of Cardiology and Brazilian Society of Exercise and Sports Medicine Updated Guidelines for Sports and Exercise Cardiology - 2019. Arq Bras Cardiol. 2019; 112(3):326-368. PMC: 6424031. DOI: 10.5935/abc.20190048. View

14.

Hernandes N, Wouters E, Meijer K, Annegarn J, Pitta F, Spruit M . Reproducibility of 6-minute walking test in patients with COPD. Eur Respir J. 2010; 38(2):261-7. DOI: 10.1183/09031936.00142010. View

15.

Vaidya T, Chambellan A, de Bisschop C . Sit-to-stand tests for COPD: A literature review. Respir Med. 2017; 128:70-77. DOI: 10.1016/j.rmed.2017.05.003. View

16.

Lima C, Dornelas de Andrade A, Campos S, Brandao D, Mourato I, Britto M . Six-minute walk test as a determinant of the functional capacity of children and adolescents with cystic fibrosis: A systematic review. Respir Med. 2018; 137:83-88. DOI: 10.1016/j.rmed.2018.02.016. View

17.

Kocks J, Asijee G, Tsiligianni I, Kerstjens H, van der Molen T . Functional status measurement in COPD: a review of available methods and their feasibility in primary care. Prim Care Respir J. 2011; 20(3):269-75. PMC: 6549845. DOI: 10.4104/pcrj.2011.00031. View

18.

Nsenga Leunkeu A, Shephard R, Ahmaidi S . Six-minute walk test in children with cerebral palsy gross motor function classification system levels I and II: reproducibility, validity, and training effects. Arch Phys Med Rehabil. 2012; 93(12):2333-9. DOI: 10.1016/j.apmr.2012.06.005. View

19.

Miller M, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A . Standardisation of spirometry. Eur Respir J. 2005; 26(2):319-38. DOI: 10.1183/09031936.05.00034805. View

20.

Morinder G, Mattsson E, Sollander C, Marcus C, Larsson U . Six-minute walk test in obese children and adolescents: reproducibility and validity. Physiother Res Int. 2008; 14(2):91-104. DOI: 10.1002/pri.428. View