Computed Tomography of Lymph Node Metastasis Before and After Radiation Therapy: Correlations With Residual Tumour

Overview

Journal In Vivo

Specialty Oncology

Date 2020 Sep 3

PMID 32871805

Citations 1

Authors

Naoya Ishibashi

Toshiya Maebayashi

Haruna Nishimaki

Masahiro Okada

Affiliations

Soon will be listed here.

Abstract

Background: Computed tomography (CT) performed after radiation therapy (RT) is used to detect residual lymph node (LN) metastasis. Here, we investigated which LN parameters on pre- and post-RT CT images correlated with residual tumour in patients with head and neck cancer.

Patients And Methods: We enrolled 23 patients who received RT. A total of 50 LNs were evaluated. Correlations between quantitative and qualitative findings and residual tumours were evaluated.

Results: The median patient age was 61 years. Thirty-one LNs were histologically confirmed to contain residual tumour. LNs with residual tumour had significantly longer short and long axes on post-RT CT images. A new finding of obscured margins after RT were significantly associated with the presence of residual tumour by univariate and multivariate analyses.

Conclusion: Comparison of qualitative, LN parameters on pre- and post-RT CT images may improve the detection of residual tumour in patients with suspected residual or recurrent LN metastasis.

Citing Articles

Development and validation of a nomogram for prediction of cervical lymph node metastasis in middle and lower thoracic esophageal squamous cell carcinoma.

Yan Z, Xu X, Lu J, You Y, Xu J, Xu T BMC Gastroenterol. 2022; 22(1):163.

PMID: 35369868 PMC: 8978436. DOI: 10.1186/s12876-022-02243-8.

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