Cardiovascular System in COVID-19: Simply a Viewer or a Leading Actor?

Overview

Journal Life (Basel)

Specialty Biology

Date 2020 Sep 2

PMID 32867137

Citations 7

Authors

Filiberto Fausto Mottola

Nicoletta Verde

Riccardo Ricciolino

Marco Di Di Mauro

Marco Giuseppe Migliaccio

Vincenzo Carfora

Giorgio Spiniello

Nicola Coppola

Vanvitelli Covid-Group

Affiliations

Soon will be listed here.

Abstract

As of January 2020, a new pandemic has spread from Wuhan and caused thousands of deaths worldwide. Several studies have observed a relationship between coronavirus disease (COVID-19) infection and the cardiovascular system with the appearance of myocardial damage, myocarditis, pericarditis, heart failure and various arrhythmic manifestations, as well as an increase in thromboembolic risk. Cardiovascular manifestations have been highlighted especially in older and more fragile patients and in those with multiple cardiovascular risk factors such as cancer, diabetes, obesity and hypertension. In this review, we will examine the cardiac involvement associated with SARS-CoV-2 infection, focusing on the pathophysiological mechanism underlying manifestations and their clinical implication, taking into account the main scientific papers published to date.

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