A Chemical Covalent Tactic for Bio-thiol Sensing and Protein Labeling Agent Design

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2020 Aug 29

PMID 32857068

Citations 2

Authors

Liangwei Zhang

Jie Kang

Shudi Liu

Xia Zhang

Jinyu Sun

Yuesong Hu

Yang Yang

Lingxin Chen

Affiliations

Soon will be listed here.

Abstract

Discovering novel chemical reactions is important for bioanalysis. Herein, we report a tactic for bio-thiol sensing and protein labeling agent design by the installation of a sulfoxide group onto the skeleton of various fluorophores, and powerfully validate its abilities, which may shed light on the development of specific protein tags to give insight into their biological functions.

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