DNA N6-Methyladenine Modification in Wild and Cultivated Soybeans Reveals Different Patterns in Nucleus and Cytoplasm

Overview

Journal Front Genet

Date 2020 Aug 28

PMID 32849778

Citations 6

Authors

De-Hui Yuan

Jian-Feng Xing

Mei-Wei Luan

Kai-Kai Ji

Jun Guo

Shang-Qian Xie

Yuan-Ming Zhang

Affiliations

Soon will be listed here.

Abstract

DNA 6mA modification, an important newly discovered epigenetic mark, plays a crucial role in organisms and has been attracting more and more attention in recent years. The soybean is economically the most important bean in the world, providing vegetable protein for millions of people. However, the distribution pattern and function of 6mA in soybean are still unknown. In this study, we decoded 6mA modification to single-nucleotide resolution in wild and cultivated soybeans, and compared the 6mA differences between cytoplasmic and nuclear genomes and between wild and cultivated soybeans. The motif of 6mA in the nuclear genome was conserved across the two kinds of soybeans, and ANHGA was the most dominant motif in wild and cultivated soybeans. Genes with 6mA modification in the nucleus had higher expression than those without modification. Interestingly, 6mA distribution patterns in cytoplasm for each soybean were significantly different from those in nucleus, which was reported for the first time in soybean. Our research provides a new insight in the deep analysis of cytoplasmic genomic DNA modification in plants.

Citing Articles

6mA DNA Methylation on Genes in Plants Is Associated with Gene Complexity, Expression and Duplication.

Zhang Y, Zhang Q, Yang X, Gu X, Chen J, Shi T Plants (Basel). 2023; 12(10).

PMID: 37653866 PMC: 10221889. DOI: 10.3390/plants12101949.

Beyond transcription factors: more regulatory layers affecting soybean gene expression under abiotic stress.

Cadavid I, Balbinott N, Margis R Genet Mol Biol. 2023; 46(1 Suppl 1):e20220166.

PMID: 36706026 PMC: 9881580. DOI: 10.1590/1678-4685-GMB-2022-0166.

Distribution Pattern of N6-Methyladenine DNA Modification in the Seashore Paspalum () Genome.

Hao J, Xing J, Hu X, Wang Z, Tang M, Liao L Front Plant Sci. 2022; 13:922152.

PMID: 35873961 PMC: 9302377. DOI: 10.3389/fpls.2022.922152.

Plant synthetic epigenomic engineering for crop improvement.

Yang L, Zhang P, Wang Y, Hu G, Guo W, Gu X Sci China Life Sci. 2022; 65(11):2191-2204.

PMID: 35851940 DOI: 10.1007/s11427-021-2131-6.

Harnessing Current Knowledge of DNA N6-Methyladenosine From Model Plants for Non-model Crops.

Chachar S, Liu J, Zhang P, Riaz A, Guan C, Liu S Front Genet. 2021; 12:668317.

PMID: 33995495 PMC: 8118384. DOI: 10.3389/fgene.2021.668317.

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