Laparoscopically Assisted Ilio-inguinal Lymph Node Dissection Versus Inguinal Lymph Node Dissection in Melanoma

Overview

Journal Melanoma Manag

Date 2020 Aug 22

PMID 32821374

Citations 1

Authors

Enrique Boldo

Araceli Mayol

Rafael Lozoya

Alba Coret

Diana Escribano

Carlos Fortea

Andres Munoz

Juan Carlos Pastor

Guillermo Perez De Lucia

Affiliations

Soon will be listed here.

Abstract

Aim: Morbidity of open inguinal lymphadenectomy (OIL) is high. We use laparoscopy for pelvic time, preservation of the greater saphenous vein and transverse inguinal incisions (laparoscopically assisted ilio-inguinal lymphadenectomy, LIIL) to improve postoperative outcomes.

Patients & Methods: Retrospective comparison of 14 patients who underwent LIIL and seven patients who underwent OIL.

Results: Fourteen LIIL compared with seven OIL showed a statistically significant reduction in morbidity (15.3 vs 75%) and hospital stay (7 vs 15.7 days). Pelvic lymph node involvement (27%) was not detected preoperatively. With a mean follow-up of 36.2 (range: 3-137) months, local recurrence rate was 58.3% in LIIL and 40% in OIL. Overall survival was significantly higher in OIL than in LIIL.

Conclusion: Compared with OIL, LIIL reduced postoperative complications and hospital stay.

Citing Articles

Nursing of Vulvar Cancer Radical Operation Combined with Laparoscopic Inguinal Lymph Node Dissection.

Huang S, Qiu F Emerg Med Int. 2022; 2022:8091114.

PMID: 36105671 PMC: 9467793. DOI: 10.1155/2022/8091114.

References

Karakousis C, Emrich L, Rao U . Groin dissection in malignant melanoma. Am J Surg. 1986; 152(5):491-5. DOI: 10.1016/0002-9610(86)90211-4. View

Soderman M, Thomsen J, Sorensen J . Complications following inguinal and ilioinguinal lymphadenectomies: a meta-analysis. J Plast Surg Hand Surg. 2016; 50(6):315-320. DOI: 10.3109/2000656X.2016.1173560. View

Ichimiya M, Goishi K, Muto M . Endoscopic groin lymph node dissection as a preferable technique for malignant skin neoplasms. J Plast Surg Hand Surg. 2013; 47(4):248-51. DOI: 10.3109/2000656X.2012.752740. View

Egger M, Brown R, Roach B, Quillo A, Martin 2nd R, Scoggins C . Addition of an iliac/obturator lymph node dissection does not improve nodal recurrence or survival in melanoma. J Am Coll Surg. 2014; 219(1):101-8. DOI: 10.1016/j.jamcollsurg.2014.02.019. View

Sommariva A, Pasquali S, Cona C, Ciccarese A, Saadeh L, Campana L . Videoscopic ilioinguinal lymphadenectomy for groin lymph node metastases from melanoma. Br J Surg. 2016; 103(8):1026-32. DOI: 10.1002/bjs.10140. View

Spillane A, Haydu L, McMillan W, Stretch J, Thompson J . Quality assurance parameters and predictors of outcome for ilioinguinal and inguinal dissection in a contemporary melanoma patient population. Ann Surg Oncol. 2011; 18(9):2521-8. DOI: 10.1245/s10434-011-1755-7. View

Faries M, Thompson J, Cochran A, Andtbacka R, Mozzillo N, Zager J . Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma. N Engl J Med. 2017; 376(23):2211-2222. PMC: 5548388. DOI: 10.1056/NEJMoa1613210. View

Rossi C, Mozzillo N, Maurichi A, Pasquali S, Macripo G, Borgognoni L . Number of excised lymph nodes as a quality assurance measure for lymphadenectomy in melanoma. JAMA Surg. 2014; 149(7):700-6. DOI: 10.1001/jamasurg.2013.5676. View

Berger-Richardson D, Cordeiro E, Ernjakovic M, Easson A . Lymph node retrieval rates in melanoma: a quality assessment parameter. Curr Oncol. 2017; 24(4):e323-e327. PMC: 5576471. DOI: 10.3747/co.24.3593. View

10.

van der Ploeg A, van Akkooi A, Schmitz P, van Geel A, de Wilt J, Eggermont A . Therapeutic surgical management of palpable melanoma groin metastases: superficial or combined superficial and deep groin lymph node dissection. Ann Surg Oncol. 2011; 18(12):3300-8. PMC: 3192282. DOI: 10.1245/s10434-011-1741-0. View

11.

Morton D . Overview and update of the phase III Multicenter Selective Lymphadenectomy Trials (MSLT-I and MSLT-II) in melanoma. Clin Exp Metastasis. 2012; 29(7):699-706. PMC: 3463679. DOI: 10.1007/s10585-012-9503-3. View

12.

Delman K, Kooby D, Ogan K, Hsiao W, Master V . Feasibility of a novel approach to inguinal lymphadenectomy: minimally invasive groin dissection for melanoma. Ann Surg Oncol. 2010; 17(3):731-7. DOI: 10.1245/s10434-009-0816-7. View

13.

Callender G, McMasters K . Early versus delayed complete lymphadenectomy in melanoma: insight from MSLT I. Ann Surg Oncol. 2010; 18(2):306-8. DOI: 10.1245/s10434-010-1481-6. View

14.

Verver D, Madu M, Oude Ophuis C, Faut M, de Wilt J, Bonenkamp J . Optimal extent of completion lymphadenectomy for patients with melanoma and a positive sentinel node in the groin. Br J Surg. 2017; 105(1):96-105. PMC: 5765473. DOI: 10.1002/bjs.10644. View

15.

Jakub J, Terando A, Sarnaik A, Ariyan C, Faries M, Zani Jr S . Safety and Feasibility of Minimally Invasive Inguinal Lymph Node Dissection in Patients With Melanoma (SAFE-MILND): Report of a Prospective Multi-institutional Trial. Ann Surg. 2016; 265(1):192-196. PMC: 4999343. DOI: 10.1097/SLA.0000000000001670. View

16.

Leiter U, Stadler R, Mauch C, Hohenberger W, Brockmeyer N, Berking C . Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial. Lancet Oncol. 2016; 17(6):757-767. DOI: 10.1016/S1470-2045(16)00141-8. View

17.

Abbott A, Grotz T, Rueth N, Hernandez Irizarry R, Tuttle T, Jakub J . Minimally invasive inguinal lymph node dissection (MILND) for melanoma: experience from two academic centers. Ann Surg Oncol. 2012; 20(1):340-5. DOI: 10.1245/s10434-012-2545-6. View

18.

Vrielink O, Faut M, Deckers E, van Leeuwen B, Been L . Evaluation of the videoscopic inguinal lymphadenectomy in melanoma patients. Eur J Surg Oncol. 2019; 45(9):1712-1716. DOI: 10.1016/j.ejso.2019.04.018. View