Nocardia Takedensis: a Newly Recognized Pathogen Responsible for Skin and Soft Tissue Infections

Overview

Journal Ann Clin Microbiol Antimicrob

Publisher Biomed Central

Specialties Infectious Diseases
Microbiology

Date 2020 Aug 22

PMID 32819355

Citations 2

Authors

Romain Lotte

Alicia Chevalier

Sabine Dantas

Nicolas Degand

Alice Gaudart

Pierre-Simon Rorhlich

Laurent Boyer

Veronica Rodriguez-Nava

Pascal Del Giudice

Raymond Ruimy

Affiliations

Soon will be listed here.

Abstract

Nocardia takedensis was first isolated in 2005, from soil in Japan. We report here two cases of lymphangitis in France (2012-2017) caused by N. takedensis both occurring after skin injury while gardening, which enabled its inoculation. The two patients were immunocompromised and successfully treated by an antimicrobial agent active on the isolated strain, trimethoprim-sulfamethoxazole and amoxicillin-clavulanic acid for patient one and patient two, respectively. Our study along with previous ones supports the idea of a newly recognized cutaneous opportunistic pathogen and reinforces the recommendation of using gloves during soil exposure for immunocompromised patients. Lastly, according to data found in the literature, we would recommend trimethoprim-sulfamethoxazole as an efficient empirical antibiotic therapy in case of cutaneous infection caused by N. takedensis.

Citing Articles

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