Sensory Transduction in Bacterial Chemotaxis Involves Phosphotransfer Between Che Proteins

Overview

Journal Biochem Biophys Res Commun

Publisher Elsevier

Specialty Biochemistry

Date 1988 Mar 15

PMID 3279958

Citations 69

Authors

D Wylie

A Stock

C Y Wong

J Stock

Affiliations

Soon will be listed here.

Abstract

The CheA protein of the Salmonella typhimurium chemotaxis system is phosphorylated by ATP. Phospho-CheA transfers its phosphoryl group to a second chemotaxis protein, CheY. Unlike phospho-CheA, phospho-CheY is relatively unstable, rapidly decaying to phosphate and CheY. We propose that phosphorylation of CheY may play a role in its function as a tumble regulator to control motor behavior in response to attractant and repellent stimuli.

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