» Articles » PMID: 32787455

Hyperthyroidism As a Precipitant Factor for Cerebral Venous Thrombosis: A Case Report

Overview
Specialty General Medicine
Date 2020 Aug 14
PMID 32787455
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

Cerebral venous sinus thrombosis (CVT) is an uncommon yet serious condition. While CVT has many known precipitants and etiologies, hyperthyroidism as a precipitant of CVT is not well understood. This study reported a case of a 41-year-old male with a 4-year history of hyperthyroidism presented with seizure. Consequently, a diagnosis of superior sagittal sinus thrombosis was confirmed by computed tomography and magnetic resonance (MR) venograms. Extensive investigations yielded no apparent underlying cause, but laboratory findings were consistent with uncontrolled hyperthyroidism. The patient improved rapidly following anticoagulation. Follow-up MR and MRV scans 2 months after treatment revealed full recanalization of the superior sagittal sinus. This case report highlighted hyperthyroidism, as a procoagulant condition, resulting specifically in superior sagittal sinus thrombosis.

Citing Articles

Association Between Thyrotoxicosis and Cerebral Venous Thrombosis.

Paccagnella M, Pizzo A, Calabro V, Velardi V, Fabris B, Bernardi S J Clin Med. 2024; 13(21).

PMID: 39518686 PMC: 11546735. DOI: 10.3390/jcm13216547.


Alcohol Emergence: A Study on Various Risk Factors and Clinical Characteristics in Patients With Cerebral Venous Sinus Thrombosis From a Tertiary Care Hospital in South India.

Murugaiyan S, Sivaji A, Julin A Cureus. 2024; 16(7):e65528.

PMID: 39188469 PMC: 11346587. DOI: 10.7759/cureus.65528.


Cerebral Venous Thrombosis during Thyrotoxicosis: Case Report and Literature Update.

Raho E, Antonioni A, Cotta Ramusino N, Jubea D, Gragnaniello D, Franceschetti P J Pers Med. 2023; 13(11).

PMID: 38003871 PMC: 10672691. DOI: 10.3390/jpm13111557.


Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review.

Theologou R, Nteveros A, Artemiadis A, Faropoulos K Life (Basel). 2023; 13(5).

PMID: 37240823 PMC: 10222108. DOI: 10.3390/life13051178.


Venous Thromboembolism and Thymic Hyperplasia in the Setting of Silent Graves' Disease.

Rayan M, Jones T, Ruiz De Villa A, Calestino M, Bazikian Y Cureus. 2022; 14(4):e23935.

PMID: 35547433 PMC: 9085705. DOI: 10.7759/cureus.23935.

References
1.
Gowda V, Nanjundappa R, Pendharkar H, Benakappa N . Homocystinuria with Cerebral Venous Sinus Thrombosis: Excellent Recovery with Intravenous Recombinant Tissue Plasminogen Activator. Iran J Child Neurol. 2017; 11(3):48-52. PMC: 5582360. View

2.
Saposnik G, Barinagarrementeria F, Brown Jr R, Bushnell C, Cucchiara B, Cushman M . Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011; 42(4):1158-92. DOI: 10.1161/STR.0b013e31820a8364. View

3.
Ferro J, Correia M, Pontes C, Baptista M, Pita F . Cerebral vein and dural sinus thrombosis in Portugal: 1980-1998. Cerebrovasc Dis. 2001; 11(3):177-82. DOI: 10.1159/000047635. View

4.
Yokoyama M, Yamashita R, Furuya M, Yamazaki M, Koyama K, Tanaka F . A Case of Cerebral Venous Thrombosis and Deep Venous Thrombosis Due to Hyperthyroidism with Increased Factor VIII Activity. J Stroke Cerebrovasc Dis. 2019; 28(11):104364. DOI: 10.1016/j.jstrokecerebrovasdis.2019.104364. View

5.
Brent G . Clinical practice. Graves' disease. N Engl J Med. 2008; 358(24):2594-605. DOI: 10.1056/NEJMcp0801880. View