» Articles » PMID: 32765742

Distress in Neurocognitive Disorders Due to Alzheimer's Disease and Stroke

Overview
Journal Exp Ther Med
Specialty Pathology
Date 2020 Aug 9
PMID 32765742
Citations 7
Authors
Affiliations
Soon will be listed here.
Abstract

Patients with neurocognitive disorders experience subjectively the concept of quality of life; this is the reason why researchers avoid approaching this concept and prefer to focus attention on the emotional profile of the caregivers. Many studies highlight the efforts both emotional and financial made by caregivers in case of patients diagnosed with neurocognitive disorders. The present study shows the differences between the patients diagnosed with neurocognitive disorder due to Alzheimer's disease and patients diagnosed with stroke, as well as the Romanian norms for the short form of Geriatric Depression Scale. The study group consisted of the clinical population (N=45), selected according to the inclusion/exclusion criteria, following the principles of Helsinki Declaration for Ethical Medical Research. The study was conducted at the Neuropsychiatry section of the Municipal Clinical Hospital, Dr Gavril Curteanu, Oradea, Romania. The results showed significant differences between the two types of patients in terms of quality of life, t(43)=-7.99, P=0.001, affective distress, t(43)=5.10, P=0.001 and perceived stress, t(43)=3.81, P=0.001. The internal consistency of the scale is high, the coefficient KR-20 being 0.86.

Citing Articles

Positive irrational beliefs are associated with hypomanic personality.

Tiba A, Trip S, Bora C, Drugas M, Borz F, Miclaus D Front Psychol. 2023; 14:1053486.

PMID: 37020915 PMC: 10067582. DOI: 10.3389/fpsyg.2023.1053486.


Analysis of Features of Alzheimer's Disease: Detection of Early Stage from Functional Brain Changes in Magnetic Resonance Images Using a Finetuned ResNet18 Network.

Odusami M, Maskeliunas R, Damasevicius R, Krilavicius T Diagnostics (Basel). 2021; 11(6).

PMID: 34200832 PMC: 8230447. DOI: 10.3390/diagnostics11061071.


The Analysis of Oxidative Stress Markers May Increase the Accuracy of the Differential Diagnosis of Alzheimer's Disease with and without Depression.

Polak-Szabela A, Dziembowska I, Bracha M, Pedrycz-Wieczorska A, Kedziora-Kornatowska K, Kozakiewicz M Clin Interv Aging. 2021; 16:1105-1117.

PMID: 34163154 PMC: 8215848. DOI: 10.2147/CIA.S310750.


Association between Serum Concentrations of Apolipoprotein A-I (ApoA-I) and Alzheimer's Disease: Systematic Review and Meta-Analysis.

Zuin M, Cervellati C, Trentini A, Passaro A, Rosta V, Zimetti F Diagnostics (Basel). 2021; 11(6).

PMID: 34071695 PMC: 8229134. DOI: 10.3390/diagnostics11060984.


Effects of Anti-Inflammatory Treatment and Surgical Intervention on Endothelial Glycocalyx, Peripheral and Coronary Microcirculatory Function and Myocardial Deformation in Inflammatory Bowel Disease Patients: A Two-Arms Two-Stage Clinical Trial.

Triantafyllou C, Nikolaou M, Ikonomidis I, Bamias G, Kouretas D, Andreadou I Diagnostics (Basel). 2021; 11(6).

PMID: 34070768 PMC: 8227308. DOI: 10.3390/diagnostics11060993.


References
1.
Mucke L . Neuroscience: Alzheimer's disease. Nature. 2009; 461(7266):895-7. DOI: 10.1038/461895a. View

2.
Abdel-Daim M, El-Tawil O, Bungau S, Atanasov A . Applications of Antioxidants in Metabolic Disorders and Degenerative Diseases: Mechanistic Approach. Oxid Med Cell Longev. 2019; 2019:4179676. PMC: 6701332. DOI: 10.1155/2019/4179676. View

3.
Jellinger K . Pathology and pathogenesis of vascular cognitive impairment-a critical update. Front Aging Neurosci. 2013; 5:17. PMC: 3622231. DOI: 10.3389/fnagi.2013.00017. View

4.
Wolstenholme J, Fenn P, Gray A, Keene J, Jacoby R, Hope T . Estimating the relationship between disease progression and cost of care in dementia. Br J Psychiatry. 2002; 181:36-42. DOI: 10.1192/bjp.181.1.36. View

5.
Aznar S, Knudsen G . Depression and Alzheimer's disease: is stress the initiating factor in a common neuropathological cascade?. J Alzheimers Dis. 2010; 23(2):177-93. DOI: 10.3233/JAD-2010-100390. View