Imaging in Primary Sjögren's Syndrome

Overview

Journal J Clin Med

Specialty General Medicine

Date 2020 Aug 7

PMID 32756395

Citations 28

Authors

Martha S van Ginkel

Andor W J M Glaudemans

Bert van der Vegt

Esther Mossel

Frans G M Kroese

Hendrika Bootsma

Arjan Vissink

Affiliations

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Abstract

Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterized by dysfunction and lymphocytic infiltration of the salivary and lacrimal glands. Besides the characteristic sicca complaints, pSS patients can present a spectrum of signs and symptoms, which challenges the diagnostic process. Various imaging techniques can be used to assist in the diagnostic work-up and follow-up of pSS patients. Developments in imaging techniques provide new opportunities and perspectives. In this descriptive review, we discuss imaging techniques that are used in pSS with a focus on the salivary glands. The emphasis is on the contribution of these techniques to the diagnosis of pSS, their potential in assessing disease activity and disease progression in pSS, and their contribution to diagnosing and staging of pSS-associated lymphomas. Imaging findings of the salivary glands will be linked to histopathological changes in the salivary glands of pSS patients.

Citing Articles

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Primary Sjögren's syndrome: new perspectives on salivary gland epithelial cells.

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Anti-centromere antibody positivity is an independent variable associated with salivary gland ultrasonography score in Sjögren's syndrome.

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Sonographic Appearance of Lacrimal Glands in Sjögren's Syndrome at High Risk for Lymphoma Development.

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