Biomechanics of Implant Fixation in Osteoporotic Bone

Overview

Journal Curr Osteoporos Rep

Publisher Current Science

Specialties Endocrinology
Orthopedics

Date 2020 Aug 1

PMID 32734511

Citations 10

Authors

Kyle D Anderson

Frank C Ko

Amarjit S Virdi

D Rick Sumner

Ryan D Ross

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: The purpose of this review is to critically evaluate the current literature regarding implant fixation in osteoporotic bone.

Recent Findings: Clinical studies have not only demonstrated the growing prevalence of osteoporosis in patients undergoing total joint replacement (TJR) but may also indicate a significant gap in screening and treatment of this comorbidity. Osteoporosis negatively impacts bone in multiple ways beyond the mere loss of bone mass, including compromising skeletal regenerative capacity, architectural deterioration, and bone matrix quality, all of which could diminish implant fixation. Recent findings both in preclinical animal models and in clinical studies indicate encouraging results for the use of osteoporosis drugs to promote implant fixation. Implant fixation in osteoporotic bone presents an increasing clinical challenge that may be benefitted by increased screening and usage of osteoporosis drugs.

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