Microwave-assisted Efficient One-pot Synthesis of -(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines

Overview

Journal Beilstein J Org Chem

Specialty Chemistry

Date 2020 Aug 1

PMID 32733614

Authors

Moustafa Sherief Moustafa

Ramadan Ahmed Mekheimer

Saleh Mohammed Al-Mousawi

Mohamed Abd-Elmonem

Hesham El-Zorba

Afaf Mohamed Abdel Hameed

Tahany Mahmoud Mohamed

Kamal Usef Sadek

Affiliations

Soon will be listed here.

Abstract

An efficient one-pot synthesis of -(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products.

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