» Articles » PMID: 32723250

An Overview of the Mechanisms of Marine Fungi-Derived Anti-Inflammatory and Anti-Tumor Agents and Their Novel Role in Drug Targeting

Overview
Journal Curr Pharm Des
Date 2020 Jul 30
PMID 32723250
Citations 20
Authors
Affiliations
Soon will be listed here.
Abstract

Marine fungi with their successful pharmacological effects were considered to be the treasure of ocean medicines concerning the striking ability of their secondary metabolites. Literature over literature has been published on fungi derived bioactive molecules to probe its therapeutic potential. Marine fungi have an implicit to cede future medicines against life-threatening diseases, such as cancer and several emerging inflammations. The biological actions of many marine fungi-derived secondary metabolites are still unlocked, for an assorted number of bioactive compounds by which they interact with human diseases are discussed here with comprehensive diagrams. This knowledge is one of the main tracks to be established specifically for the successful transformation of bioactive compounds to medicines. Marine fungi produce a diverse range of biochemical substances with precious carbon scaffolds, which are the main component interplaying with human diseases at distinctive spots. Specific diseases having a flair to fight at distinctive targets within the body can lead to a new trend of raising the chances of developing targeted drugs.

Citing Articles

Plant and marine-derived natural products: sustainable pathways for future drug discovery and therapeutic development.

Ahmad M, Tahir M, Hong Z, Zia M, Rafeeq H, Ahmad M Front Pharmacol. 2025; 15():1497668.

PMID: 39834812 PMC: 11743463. DOI: 10.3389/fphar.2024.1497668.


NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice.

Ali M, Ullah H, Farooqui N, Deng T, Siddiqui N, Ilyas M Heliyon. 2024; 10(19):e38370.

PMID: 39403534 PMC: 11472078. DOI: 10.1016/j.heliyon.2024.e38370.


Solamargine induces apoptosis of human renal carcinoma cells via downregulating phosphorylated STAT3 expression.

Huang S, Sun M, Ren Y, Luo T, Wang X, Weng G Oncol Lett. 2023; 26(5):493.

PMID: 37854861 PMC: 10579987. DOI: 10.3892/ol.2023.14080.


Chemical Compositions and Experimental and Computational Modeling of the Anticancer Effects of Cnidocyte Venoms of Jellyfish and on Human Adenocarcinoma A549 Cells.

Zare A, Afshar A, Khoradmehr A, Baghban N, Mohebbi G, Barmak A Mar Drugs. 2023; 21(3).

PMID: 36976217 PMC: 10057638. DOI: 10.3390/md21030168.


Applications of Extracellular Vesicles in Nervous System Disorders: An Overview of Recent Advances.

Ullah Khan S, Khan M, Khan M, Khan N, Bungau S, Hassan S Bioengineering (Basel). 2023; 10(1).

PMID: 36671622 PMC: 9854809. DOI: 10.3390/bioengineering10010051.