Antisynthetase Syndrome in Pregnancy: A Case and Review of the Literature

Overview

Journal Obstet Med

Specialty Gynecology & Obstetrics

Date 2020 Jul 28

PMID 32714443

Citations 3

Authors

Lauren J Green

Lorraine ONeill

Charlotte J Frise

Affiliations

Soon will be listed here.

Abstract

Antisynthetase syndrome is a rare autoimmune, multisystem, inflammatory condition, characterised by autoantibodies against aminoacyl tRNA synthetases. The predominant features are myositis and interstitial lung disease but other symptoms such as Raynaud's phenomenon may also be present. Described here is a 36-year-old woman with antisynthetase syndrome who planned and underwent a successful pregnancy, during which a multidisciplinary team approach secured a good outcome for both mother and baby.

Citing Articles

A 25-Year-Old Saudi Woman with a 2-Year History of Antisynthetase Syndrome with Interstitial Lung Disease Who Commenced Azathioprine Treatment in the Third Trimester of Pregnancy and Had a Successful Birth at Term.

Alshwairikh L, Babay Z Am J Case Rep. 2022; 23:e936833.

PMID: 35794813 PMC: 9274784. DOI: 10.12659/AJCR.936833.

Antisynthetase Syndrome with Severe Interstitial Lung Disease in Pregnancy.

Dumitrascu C, Olsen D, Arendt K, Rose C, Sharpe E Case Rep Anesthesiol. 2021; 2021:1150394.

PMID: 34350037 PMC: 8328709. DOI: 10.1155/2021/1150394.

Premature live birth in a woman with antisynthetase syndrome following recurrent miscarriages.

Kowitz M, Chakradeo K, Hennessey A, Wolski P BMJ Case Rep. 2021; 14(5).

PMID: 33975837 PMC: 8117991. DOI: 10.1136/bcr-2020-240929.

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