Pediatric Obesity: Prevention is Better Than Care

Overview

Journal Ital J Pediatr

Publisher Biomed Central

Specialty Pediatrics

Date 2020 Jul 26

PMID 32709246

Citations 14

Authors

Roberta Romanelli

Nicola Cecchi

Maria Grazia Carbone

Michele Dinardo

Giuseppina Gaudino

Emanuele Miraglia Del Giudice

Giuseppina Rosaria Umano

Affiliations

Soon will be listed here.

Abstract

Pediatric obesity is one of the most relevant health issues of the last century. Obesity-related short and long-term consequences are responsible of a large amount of economic cost. In addition, the different therapeutic strategies, such as lifestyle correction, drug, and bariatric surgery have displayed low effectiveness. Considering this evidence, prevention appears to be more promising than treatment in contrasting obesity epidemic. In this review, we summarize obesity pathogenesis with the aim of highlight the main obesity risk factors that can be addressed as target of preventive interventions. Moreover, we report the evidence about effectiveness of different interventions targeting family, school, and community. A multiple-component intervention, addressing different targets and settings, might be desirable, however more studies are needed to confirm long-term efficacy and to direct policy interventions.

Citing Articles

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References

Gortmaker S, Wang Y, Long M, Giles C, Ward Z, Barrett J . Three Interventions That Reduce Childhood Obesity Are Projected To Save More Than They Cost To Implement. Health Aff (Millwood). 2015; 34(11):1932-9. PMC: 9627551. DOI: 10.1377/hlthaff.2015.0631. View

Lutfiyya M, Lipsky M, Wisdom-Behounek J, Inpanbutr-Martinkus M . Is rural residency a risk factor for overweight and obesity for U.S. children?. Obesity (Silver Spring). 2007; 15(9):2348-56. DOI: 10.1038/oby.2007.278. View

Sundborn G, Thornley S, Beaglehole R, Bezzant N . Policy brief: a sugary drink tax for New Zealand and 10,000-strong petition snubbed by Minister of Health and National Government. N Z Med J. 2017; 130(1462):114-116. View

Victora C, Bahl R, Barros A, Franca G, Horton S, Krasevec J . Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect. Lancet. 2016; 387(10017):475-90. DOI: 10.1016/S0140-6736(15)01024-7. View

Herrera B, Keildson S, Lindgren C . Genetics and epigenetics of obesity. Maturitas. 2011; 69(1):41-9. PMC: 3213306. DOI: 10.1016/j.maturitas.2011.02.018. View

Dao M, Clement K . Gut microbiota and obesity: Concepts relevant to clinical care. Eur J Intern Med. 2017; 48:18-24. DOI: 10.1016/j.ejim.2017.10.005. View

Azad M, Konya T, Maughan H, Guttman D, Field C, Chari R . Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months. CMAJ. 2013; 185(5):385-94. PMC: 3602254. DOI: 10.1503/cmaj.121189. View

Freedman D, Mei Z, Srinivasan S, Berenson G, Dietz W . Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study. J Pediatr. 2006; 150(1):12-17.e2. DOI: 10.1016/j.jpeds.2006.08.042. View

Bleich S, Vercammen K, Zatz L, Frelier J, Ebbeling C, Peeters A . Interventions to prevent global childhood overweight and obesity: a systematic review. Lancet Diabetes Endocrinol. 2017; 6(4):332-346. DOI: 10.1016/S2213-8587(17)30358-3. View

10.

Suarez-Zamorano N, Fabbiano S, Chevalier C, Stojanovic O, Colin D, Stevanovic A . Microbiota depletion promotes browning of white adipose tissue and reduces obesity. Nat Med. 2015; 21(12):1497-1501. PMC: 4675088. DOI: 10.1038/nm.3994. View

11.

Strauss W, Nagaraja J, Landgraf A, Arteaga S, Fawcett S, Ritchie L . The longitudinal relationship between community programmes and policies to prevent childhood obesity and BMI in children: the Healthy Communities Study. Pediatr Obes. 2018; 13 Suppl 1:82-92. DOI: 10.1111/ijpo.12266. View

12.

Shungin D, Winkler T, Croteau-Chonka D, Ferreira T, Locke A, Magi R . New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015; 518(7538):187-196. PMC: 4338562. DOI: 10.1038/nature14132. View

13.

Ford C, Poti J, Ng S, Popkin B . SSB taxes and diet quality in US preschoolers: estimated changes in the 2010 Healthy Eating Index. Pediatr Obes. 2016; 12(2):146-154. PMC: 5052098. DOI: 10.1111/ijpo.12121. View

14.

van Meer F, van der Laan L, Charbonnier L, Viergever M, Adan R, Smeets P . Developmental differences in the brain response to unhealthy food cues: an fMRI study of children and adults. Am J Clin Nutr. 2016; 104(6):1515-1522. DOI: 10.3945/ajcn.116.137240. View

15.

van Dijk S, Molloy P, Varinli H, Morrison J, Muhlhausler B . Epigenetics and human obesity. Int J Obes (Lond). 2014; 39(1):85-97. DOI: 10.1038/ijo.2014.34. View

16.

Brown C, Perrin E . Obesity Prevention and Treatment in Primary Care. Acad Pediatr. 2018; 18(7):736-745. DOI: 10.1016/j.acap.2018.05.004. View

17.

Miller C, Dono J, Wakefield M, Pettigrew S, Coveney J, Roder D . Are Australians ready for warning labels, marketing bans and sugary drink taxes? Two cross-sectional surveys measuring support for policy responses to sugar-sweetened beverages. BMJ Open. 2019; 9(6):e027962. PMC: 6597645. DOI: 10.1136/bmjopen-2018-027962. View

18.

McCarthy M . Soda tax brings sharp fall in sugary drink consumption in Californian city. BMJ. 2016; 355:i5940. DOI: 10.1136/bmj.i5940. View

19.

Popkin B, Gordon-Larsen P . The nutrition transition: worldwide obesity dynamics and their determinants. Int J Obes Relat Metab Disord. 2004; 28 Suppl 3:S2-9. DOI: 10.1038/sj.ijo.0802804. View

20.

Bjerregaard L, Baker J . Change in Overweight from Childhood to Early Adulthood and Risk of Type 2 Diabetes. N Engl J Med. 2018; 378(26):2537-2538. DOI: 10.1056/NEJMc1805984. View