A Green Approach Towards Native Collagen Scaffolds: Environmental and Physicochemical Assessment

Overview

Journal Polymers (Basel)

Publisher MDPI

Date 2020 Jul 26

PMID 32708371

Citations 8

Authors

Mireia Andonegi

Ainhoa Irastorza

Ander Izeta

Sara Cabezudo

Koro de la Caba

Pedro Guerrero

Affiliations

Soon will be listed here.

Abstract

Native collagen scaffolds were prepared in this work, in which both materials and environmental approaches were considered with the aim of providing a global strategy towards more sustainable biomaterials. From the environmental perspective, it is worth mentioning that acid and enzymatic treatments have been avoided to extract collagen, allowing the reduction in the use of resources, in terms of chemicals, energy, and time, and leading to a low environmental load of this step in all the impact categories under analysis. With the incorporation of chitosan into the scaffold-forming formulations, physical interactions occurred between collagen and chitosan, but the native collagen structure was preserved, as observed by Fourier transform infrared (FTIR) and X-ray diffraction (XRD) analyses. The incorporation of chitosan also led to more homogenous porous microstructures, with higher elastic moduli and compression resistance for both dry and hydrated scaffolds. Furthermore, hydrated scaffolds preserved their size and shape after some compression cycles.

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