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Young Onset Parkinson's Disease: A Modern and Tailored Approach

Overview
Journal J Parkinsons Dis
Publisher Sage Publications
Specialty Neurology
Date 2020 Jul 12
PMID 32651336
Citations 34
Authors
Bart Post
Lieneke van den Heuvel
Teije van Prooije
Xander van Ruissen
Bart van de Warrenburg
Jorik Nonnekes
Affiliations
Soon will be listed here.
Abstract

In people with young onset Parkinson's disease (YOPD), onset of symptoms is between 21 and 40 years of age. The distinction between YOPD and late-onset Parkinson's disease is supported by genetic differences (a genetic etiology is more common in people with YOPD) and clinical differences (e.g., dystonia and levodopa-induced dyskinesias are more common inYOPD). Moreover, people with YOPD tend to have different family and societal engagements compared to those with late-onset PD. These unique features have implications for clinical management, and call for a tailored multidisplinary approach involving shared-decision making.

Citing Articles

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Associations between cognitive screening performance and motor symptoms in Parkinson's disease:a systematic review and meta-analysis.

Patrick K, Cousins E, Spitznagel M Dement Neuropsychol. 2024; 18:e20230102.

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Differentiation in theta and gamma activation in weight-shifting learning between people with parkinson's disease of different anxiety severities.

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Unveiling the invisible: a qualitative interview study on the impact of young onset Parkinson's disease on (ex-partners).

Kapelle W, Geerlings A, Mutsaers I, Bloem B, Meinders M, Post B J Neurol. 2024; 271(8):5312-5325.

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