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Equity in Genomics: A Brief Report on Cardiovascular Health Disparities in African American Adults

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Date 2020 Jul 11
PMID 32649378
Citations 2
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Abstract

Background: African Americans are more likely to die from cardiovascular disease (CVD) than all other populations in the United States. Although technological advances have supported rapid growth in applying genetics/genomics to address CVD, most research has been conducted among European Americans. The lack of African American representation in genomic samples has limited progress in equitably applying precision medicine tools, which will widen CVD disparities if not remedied.

Purpose: This report summarizes the genetic/genomic advances that inform precision health and the implications for cardiovascular disparities in African American adults. We provide nurse scientists recommendations for becoming leaders in developing precision health tools that promote population health equity.

Conclusions: Genomics will continue to drive advances in CVD prevention and management, and equitable progress is imperative. Nursing should leverage the public's trust and its widespread presence in clinical and community settings to prevent the worsening of CVD disparities among African Americans.

Citing Articles

Nursing strategies to address health disparities in genomics-informed care: a scoping review.

Limoges J, Chiu P, Dordunoo D, Puddester R, Pike A, Wonsiak T JBI Evid Synth. 2024; 22(11):2267-2312.

PMID: 39258479 PMC: 11554251. DOI: 10.11124/JBIES-24-00009.


Genomics-informed nursing strategies and health equity: A scoping review protocol.

Dordunoo D, Limoges J, Chiu P, Puddester R, Carlsson L, Pike A PLoS One. 2023; 18(12):e0295914.

PMID: 38100433 PMC: 10723661. DOI: 10.1371/journal.pone.0295914.

References
1.
Visscher P, Wray N, Zhang Q, Sklar P, McCarthy M, Brown M . 10 Years of GWAS Discovery: Biology, Function, and Translation. Am J Hum Genet. 2017; 101(1):5-22. PMC: 5501872. DOI: 10.1016/j.ajhg.2017.06.005. View

2.
Williams J, Bonham V, Wicklund C, Coleman B, Taylor J, Cashion A . Advocacy and actions to address disparities in access to genomic health care: A report on a National Academies workshop. Nurs Outlook. 2019; 67(5):605-612. PMC: 9450511. DOI: 10.1016/j.outlook.2019.06.004. View

3.
Piano M, Artinian N, DeVon H, Pressler S, Hickey K, Chyun D . Cardiovascular Nursing Science Priorities: A Statement From the American Heart Association Council on Cardiovascular and Stroke Nursing. J Cardiovasc Nurs. 2018; 33(4):E11-E20. DOI: 10.1097/JCN.0000000000000489. View

4.
Kerath S, Klein G, Kern M, Shapira I, Witthuhn J, Norohna N . Beliefs and attitudes towards participating in genetic research - a population based cross-sectional study. BMC Public Health. 2013; 13:114. PMC: 3568732. DOI: 10.1186/1471-2458-13-114. View

5.
Wojczynski M, Li M, Bielak L, Kerr K, Reiner A, Wong N . Genetics of coronary artery calcification among African Americans, a meta-analysis. BMC Med Genet. 2013; 14:75. PMC: 3733595. DOI: 10.1186/1471-2350-14-75. View