» Articles » PMID: 32644864

Aggressive Angiomyxoma in Pregnancy: a Case Report and Literature Review

Overview
Journal J Int Med Res
Publisher Sage Publications
Specialty General Medicine
Date 2020 Jul 10
PMID 32644864
Citations 14
Authors
Affiliations
Soon will be listed here.
Abstract

Aggressive angiomyxoma is an interstitial tumour that is often misdiagnosed and is likely to recur. There have been few reported cases of angiomyxoma in pregnant women. We report a case of a woman who was previously diagnosed with a tumour in her vulva that increased in size during both of her pregnancies and spontaneously decreased postpartum. Local excision was performed and a gonadotropin-releasing hormone agonist was administered. According to a literature review, aggressive angiomyxoma is associated with good maternal and child outcomes. Caesarean section is not the delivery method of choice, but it is indicated if the tumour is preventing vaginal birth. Treatment for angiomyxoma is mainly postpartum local resection supplemented by hormone therapy. This tumour frequently recurs and patients should undergo long-term follow-up.

Citing Articles

Aggressive angiomyxoma of the vagina: A case report and literature review.

Yu B, Choi W, Cho D, Lee N Medicine (Baltimore). 2025; 104(4):e41287.

PMID: 39854765 PMC: 11771726. DOI: 10.1097/MD.0000000000041287.


Imaging features of a rare giant intra-abdominal aggressive angiomyxoma.

Tuan T, Trang B, Chau N, Duy N, Anh N, Hung N Radiol Case Rep. 2024; 19(9):4007-4011.

PMID: 39044857 PMC: 11263912. DOI: 10.1016/j.radcr.2024.06.041.


Aggressive Angiomyxoma of the Lower Female Genital Tract: A Review of the MITO Rare Tumors Group.

Dellino M, Magazzino F, Domenici L, Cicogna S, Miano S, Pignata S Cancers (Basel). 2024; 16(7).

PMID: 38611053 PMC: 11011140. DOI: 10.3390/cancers16071375.


Prepubertal Female Bartholin's Gland Abscess: A Comprehensive Case Report Study.

Alsayed A, Elkadi T, Alshamari M, Attallah A Case Rep Pediatr. 2024; 2024:8812350.

PMID: 38601474 PMC: 11006452. DOI: 10.1155/2024/8812350.


Deep (aggressive) angiomyxoma of the vulva in a pregnant woman.

Smet C, Martins A, Costa T BMJ Case Rep. 2023; 16(12).

PMID: 38129079 DOI: 10.1136/bcr-2023-254564.


References
1.
Sinha V, Dave K, Bhansali R, Arora R . Aggressive angiomyxoma of vulva which grew with pregnancy and attained a huge size rarely seen in literature. J Obstet Gynaecol India. 2014; 64(Suppl 1):90-1. PMC: 4228020. DOI: 10.1007/s13224-012-0338-2. View

2.
Zangmo R, Kumar S, Singh N, Meena J . Aggressive Angiomyxoma of Vulva in Pregnancy: A Case Report. J Obstet Gynaecol India. 2016; 66(Suppl 2):610-612. PMC: 5080253. DOI: 10.1007/s13224-016-0870-6. View

3.
Han-Geurts I, van Geel A, van Doorn L, M den Bakker , Eggermont A, Verhoef C . Aggressive angiomyxoma: multimodality treatments can avoid mutilating surgery. Eur J Surg Oncol. 2006; 32(10):1217-21. DOI: 10.1016/j.ejso.2006.06.008. View

4.
Haldar K, Martinek I, Kehoe S . Aggressive angiomyxoma: a case series and literature review. Eur J Surg Oncol. 2009; 36(4):335-9. DOI: 10.1016/j.ejso.2009.11.006. View

5.
Bagga R, Keepanasseril A, Suri V, Nijhawan R . Aggressive angiomyxoma of the vulva in pregnancy: a case report and review of management options. MedGenMed. 2007; 9(1):16. PMC: 1925027. View