Diet: A Specific Part of the Western Lifestyle Pack in the Asthma Epidemic
Overview
Affiliations
The Western lifestyle is a complex concept that includes the diet as the main axis of different factors which contribute to a detrimental effect on health, lower life expectancy and low quality-of-life. This type of diet is characterized by being high in calories, mainly provided by saturated fats, and rich in sugars that can lead to changes in immune cells and their responsiveness, by different mechanisms that have yet to be totally clarified. Inflammatory processes are perpetuated through different pathways, in which adipose tissue is a major factor. High fat stores in overweight and obesity accumulate energy but the endocrine function is also producing and releasing different bioactive compounds, adipokines, known to be pro-inflammatory and which play an important role in the pathogenesis of asthma. This review therefore explores the latest evidence regarding the adverse effect of the Western diet on adipose tissue inflammation and its causative effect on the asthma epidemic.
The Etiology of IgE-Mediated Food Allergy: Potential Therapeutics and Challenges.
Carnazza M, Werner R, Tiwari R, Geliebter J, Li X, Yang N Int J Mol Sci. 2025; 26(4).
PMID: 40004029 PMC: 11855496. DOI: 10.3390/ijms26041563.
Liu Z, Chen Y, Chen C, Wang C, Li M, Guo Y Nutrients. 2024; 16(16).
PMID: 39203827 PMC: 11356979. DOI: 10.3390/nu16162691.
Gut-lung axis and asthma: A historical review on mechanism and future perspective.
Song X, Liang J, Lin S, Xie Y, Ke C, Ao D Clin Transl Allergy. 2024; 14(5):e12356.
PMID: 38687096 PMC: 11060082. DOI: 10.1002/clt2.12356.
Kontopoulou L, Kotsiou O, Tourlakopoulos K, Karpetas G, Paraskevadaki E, Malli F J Pers Med. 2023; 13(10).
PMID: 37888123 PMC: 10608726. DOI: 10.3390/jpm13101512.
Fekete M, Csipo T, Fazekas-Pongor V, Balint M, Csizmadia Z, Tarantini S Nutrients. 2023; 15(18).
PMID: 37764686 PMC: 10536642. DOI: 10.3390/nu15183902.