Restoration of Foveal Bulge After Resolution of Diabetic Macular Edema with Coexisting Serous Retinal Detachment

Overview

Journal J Diabetes Res

Publisher Wiley

Specialty Endocrinology

Date 2020 Jul 7

PMID 32626784

Citations 2

Authors

Yijun Hu

Qiaowei Wu

Baoyi Liu

Manqing Huang

Qingsheng Peng

Pingting Zhong

Xiaomin Zeng

Yu Xiao

Cong Li

Ying Fang

Tao Li

Honghua Yu

Xiaohong Yang

Affiliations

Soon will be listed here.

Abstract

Purpose: To evaluate the impact of restoration of foveal bulge (FB) in optical coherence tomography (OCT) images on visual acuity after resolution of diabetic macular edema with coexisting serous retinal detachment (SRD-DME).

Methods: A total of 52 eyes with resolved SRD-DME and an intact ellipsoid zone at the central fovea were included. All eyes underwent best-corrected visual acuity (BCVA) examination and OCT scanning at baseline and follow-up visits (1, 3, and 6 months). The eyes were divided into two groups according to the presence of FB at 6 months. BCVA, central foveal thickness (CFT), height of SRD (SRDH), outer nuclear layer (ONL) thickness, photoreceptor inner segment (PIS), and outer segment (POS) length were compared between the two groups.

Results: A FB was found in 25 of 52 (48%) eyes at 6 months. The FB (+) group had lower SRDH at baseline, and better BCVA, longer POS length at 6 months (all < 0.05). There was no significant difference in the CFT, ONL thickness, and PIS length at 6 months between the two groups (all > 0.05). More eyes in the FB (+) group had complete SRD resolution at 1 month ( = 0.009) and 3 months ( = 0.012). Eyes with complete SRD resolution at 1 month ( = 0.009) or 3 months ( = 0.012) were more likely to have a FB at 6 months.

Conclusions: The Presence of the FB is associated with better BCVA after resolution of SRD-DME. Eyes with lower baseline SRDH or faster SRD resolution are more likely to have a FB at 6 months.

Citing Articles

Real-World Evidence in the Management of Diabetic Macular Edema with Intravitreal Anti-VEGFs in Asia: A Systematic Literature Review.

Yuen Y, Wei Tan G, Gan N, Too I, Mothe R, Basa P Clin Ophthalmol. 2022; 16:3503-3526.

PMID: 36274678 PMC: 9579008. DOI: 10.2147/OPTH.S378392.

Factors Associated With the Presence of Foveal Bulge in Eyes With Resolved Diabetic Macular Edema.

Wu Q, Hu Y, Liu B, Lin Z, Xiao Y, Zeng X Front Med (Lausanne). 2022; 8:755609.

PMID: 35071259 PMC: 8776985. DOI: 10.3389/fmed.2021.755609.

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