Retinal Nerve Fibre Layer Thickness Change After CO2 Laser-Assisted Deep Sclerectomy Surgery

Overview

Journal Clin Ophthalmol

Publisher Dove Medical Press

Specialty Ophthalmology

Date 2020 Jul 3

PMID 32612350

Citations 1

Authors

Zoltan Sohajda

Noemi Szell

Agnes Revak

Julia Papp

Edit Toth-Molnar

Affiliations

Soon will be listed here.

Abstract

Purpose: The goal of our study was to investigate changes in intraocular pressure (IOP), best-corrected visual acuity (BCVA), and retinal nerve fibre layer thickness (RNFLT) after CO2 laser-assisted deep sclerectomy (CLASS).

Methods: We carried out uncomplicated CLASS surgeries and a 12-month follow-up on 22 open-angle glaucomatous (OAG) eyes of 22 patients. IOP, BCVA, and RNFLT with spectral-domain optical coherence tomography (SD OCT) were recorded before and 1, 3, 6, 12 months after surgery.

Results: Mean age of patients was 68.1 years. IOP decreased from preoperative 28.45±5.99 SD mmHg (mean±standard deviation) to 15.09±2.40 mmHg (p=0.00039) at 12 months after surgery. BCVA-change from preoperative 0.34±0.38 SD (LogMAR) to 0.37±0.41 SD (LogMAR) was not significant (p=0.2456). RNFLT-change from preoperative 60.50±18.15µm to 59.63±17.52 µm at 12 months postoperatively was not significant (p=0.056). Qualified success rate of CLASS surgery was 72.7%, whereas complete success rate was 64% at 1 year postoperatively.

Conclusion: Successful CLASS surgery efficiently reduced IOP. At postoperative 12 months, RNFLT and BCVA were not reduced significantly. There was no significant glaucomatous progression after surgery encountered in respect of investigated parameters.

Citing Articles

An overview and update of CO laser‑assisted sclerectomy surgery in primary open angle glaucoma (Review).

Huang C, Shen X, Chen M, Wang K Exp Ther Med. 2023; 25(6):270.

PMID: 37206549 PMC: 10189749. DOI: 10.3892/etm.2023.11969.

Reply: efficacy and safety of CO2 laser-assisted sclerectomy surgery for glaucoma: a systematic review and meta-analysis.

Dai L, Li A, Yu L, Ye J Arq Bras Oftalmol. 2021; 84(4):418-420.

PMID: 34287524 PMC: 11826619. DOI: 10.5935/0004-2749.202100111.

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