Increase in the Risk of Type 2 Diabetes During Lockdown for the COVID19 Pandemic in India: A Cohort Analysis

Overview

Journal Diabetes Metab Syndr

Specialty Endocrinology

Date 2020 Jul 1

PMID 32604013

Citations 41

Authors

Samit Ghosal

Bhavya Arora

Koel Dutta

Amerta Ghosh

Binayak Sinha

Anoop Misra

Affiliations

Soon will be listed here.

Abstract

Material Methods: Baseline demographic and clinical data from 100 apparently non-diabetic household members (related or unrelated) of patients with type 2 diabetes mellitus were collected until 49 days of lockdown and analyzed using the XL-STAT statistical software. A two-pronged analytical strategy was employed. First, the metabolic risk profile related to age, sex, weight, family history, and exercise pattern was analyzed. This was followed by an assessment of the risk of developing type 2 diabetes using an established risk assessment engine.

Results: There was a trend towards weight gain seen in 40% of the cohort, with 16% of the population experiencing a 2.1-5 kg weight increment. When all the risk parameters were analyzed together using the ADA risk engine, there was an increase in the ADA diabetes risk score in 7% of the population, with 6.66% in the high-risk group. There was a further increase in weight among 3% of the population who were already obese at baseline.

Conclusion: We show an increased risk of T2MD consequent to weight gain during 49 days of lockdown in India.

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References

Bang H, Edwards A, Bomback A, Ballantyne C, Brillon D, Callahan M . Development and validation of a patient self-assessment score for diabetes risk. Ann Intern Med. 2009; 151(11):775-83. PMC: 3633111. DOI: 10.7326/0003-4819-151-11-200912010-00005. View

Anderson R, Heesterbeek H, Klinkenberg D, Hollingsworth T . How will country-based mitigation measures influence the course of the COVID-19 epidemic?. Lancet. 2020; 395(10228):931-934. PMC: 7158572. DOI: 10.1016/S0140-6736(20)30567-5. View

Nicola M, Alsafi Z, Sohrabi C, Kerwan A, Al-Jabir A, Iosifidis C . The socio-economic implications of the coronavirus pandemic (COVID-19): A review. Int J Surg. 2020; 78:185-193. PMC: 7162753. DOI: 10.1016/j.ijsu.2020.04.018. View

Ford E, Williamson D, Liu S . Weight change and diabetes incidence: findings from a national cohort of US adults. Am J Epidemiol. 1997; 146(3):214-22. DOI: 10.1093/oxfordjournals.aje.a009256. View

Fruhbeck G, Baker J, Busetto L, Dicker D, Goossens G, Halford J . European Association for the Study of Obesity Position Statement on the Global COVID-19 Pandemic. Obes Facts. 2020; 13(2):292-296. PMC: 7250342. DOI: 10.1159/000508082. View

Zhang Y, Ma Z . Impact of the COVID-19 Pandemic on Mental Health and Quality of Life among Local Residents in Liaoning Province, China: A Cross-Sectional Study. Int J Environ Res Public Health. 2020; 17(7). PMC: 7177660. DOI: 10.3390/ijerph17072381. View

Shrivastava U, Misra A, Mohan V, Unnikrishnan R, Bachani D . Obesity, Diabetes and Cardiovascular Diseases in India: Public Health Challenges. Curr Diabetes Rev. 2016; 13(1):65-80. DOI: 10.2174/1573399812666160805153328. View

Sattar N, Gill J . Type 2 diabetes in migrant south Asians: mechanisms, mitigation, and management. Lancet Diabetes Endocrinol. 2015; 3(12):1004-16. DOI: 10.1016/S2213-8587(15)00326-5. View

Ghosal S, Sinha B, Majumder M, Misra A . Estimation of effects of nationwide lockdown for containing coronavirus infection on worsening of glycosylated haemoglobin and increase in diabetes-related complications: A simulation model using multivariate regression analysis. Diabetes Metab Syndr. 2020; 14(4):319-323. PMC: 7146694. DOI: 10.1016/j.dsx.2020.03.014. View

10.

Rundle A, Park Y, Herbstman J, Kinsey E, Wang Y . COVID-19-Related School Closings and Risk of Weight Gain Among Children. Obesity (Silver Spring). 2020; 28(6):1008-1009. PMC: 7440663. DOI: 10.1002/oby.22813. View

11.

Resnick H, Valsania P, Halter J, Lin X . Relation of weight gain and weight loss on subsequent diabetes risk in overweight adults. J Epidemiol Community Health. 2000; 54(8):596-602. PMC: 1731720. DOI: 10.1136/jech.54.8.596. View

12.

Gomez-Hernandez A, Beneit N, Diaz-Castroverde S, Escribano O . Differential Role of Adipose Tissues in Obesity and Related Metabolic and Vascular Complications. Int J Endocrinol. 2016; 2016:1216783. PMC: 5059561. DOI: 10.1155/2016/1216783. View

13.

Tobias A . Evaluation of the lockdowns for the SARS-CoV-2 epidemic in Italy and Spain after one month follow up. Sci Total Environ. 2020; 725:138539. PMC: 7195141. DOI: 10.1016/j.scitotenv.2020.138539. View

14.

Simonnet A, Chetboun M, Poissy J, Raverdy V, Noulette J, Duhamel A . High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Requiring Invasive Mechanical Ventilation. Obesity (Silver Spring). 2020; 28(7):1195-1199. PMC: 7262326. DOI: 10.1002/oby.22831. View

15.

Zhang Y, Geng X, Tan Y, Li Q, Xu C, Xu J . New understanding of the damage of SARS-CoV-2 infection outside the respiratory system. Biomed Pharmacother. 2020; 127:110195. PMC: 7186209. DOI: 10.1016/j.biopha.2020.110195. View

16.

Ghosh A, Arora B, Gupta R, Anoop S, Misra A . Effects of nationwide lockdown during COVID-19 epidemic on lifestyle and other medical issues of patients with type 2 diabetes in north India. Diabetes Metab Syndr. 2020; 14(5):917-920. PMC: 7265851. DOI: 10.1016/j.dsx.2020.05.044. View

17.

Misra A, Sattar N, Tandon N, Shrivastava U, Vikram N, Khunti K . Clinical management of type 2 diabetes in south Asia. Lancet Diabetes Endocrinol. 2018; 6(12):979-991. DOI: 10.1016/S2213-8587(18)30199-2. View