Repeated Triplets Complicated by Monochorionic Diamniotic Twins Following Assisted Reproduction: a Case Report and Literature Review

Overview

Journal BMC Pregnancy Childbirth

Publisher Biomed Central

Specialty Gynecology & Obstetrics

Date 2020 Jun 25

PMID 32576252

Citations 1

Authors

Bing Song

Zhe Wang

Yujie Chen

Chao Wang

Zhaolian Wei

Xiaojin He

Yunxia Cao

Affiliations

Soon will be listed here.

Abstract

Background: Monochorionic twinning involves numerous maternal and fetal complications, triplets complicated by a monochorionic pair are at further increased risk. Here, we report a case of repeated triplets complicated by monochorionic diamniotic twins with successful pregnancy outcomes in a woman using autologous oocytes.

Case Presentation: A 30-year-old female undergoing embryo transfer with fresh and frozen embryo cycles with autologous oocytes. The two cycles were confirmed by transvaginal ultrasound to result in successful clinical pregnancies of triplets complicated by a monochorionic twinning. The first pregnancy resulted in a singleton delivery after a selective reduction of the monochorionic pair. The subsequent pregnancy resulted in a dichorionic diamniotic twin pregnancy after the heartbeat of one of the monochorionic twin fetuses stopped at 43 days after embryo transfer. Both of the pregnancies ended with successful live births.

Conclusions: Our case report of repeated triplets with monochorionic twins suggests the potential causes and risk factors of monochorionic twinning in assisted reproduction and raises concern regarding the timing of multifetal pregnancy reduction.

Citing Articles

Pregnancy and obstetric outcomes of dichorionic and trichorionic triamniotic triplet pregnancy with multifetal pregnancy reduction: a retrospective analysis study.

Liu S, Li G, Wang C, Zhou P, Wei Z, Song B BMC Pregnancy Childbirth. 2022; 22(1):280.

PMID: 35382798 PMC: 8985266. DOI: 10.1186/s12884-022-04617-y.

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