COVID-19 and the Endothelium

Overview

Journal Clin Hemorheol Microcirc

Publisher Sage Publications

Date 2020 Jun 23

PMID 32568187

Citations 43

Authors

F Jung

A Kruger-Genge

R P Franke

F Hufert

J-H Kupper

Affiliations

Soon will be listed here.

Abstract

There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a generalized inflammatory state and complement elements may together contribute to the overall pro-coagulative state described in COVID-19 patients leading to venular as well as to arteriolar occlusions.

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