Infection by Hepatitis Delta Virus

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2020 Jun 21

PMID 32560053

Citations 26

Authors

John M Taylor

Affiliations

Soon will be listed here.

Abstract

Hepatitis delta virus (HDV) and hepatitis B virus (HBV) are blood-borne viruses that infect human hepatocytes and cause significant liver disease. Infections with HBV are more damaging when there is a coinfection with HDV. The genomes and modes of replication of these two viruses are fundamentally different, except for the fact that, in nature, HDV replication is dependent upon the envelope proteins of HBV to achieve assembly and release of infectious virus particles, ones that use the same host cell receptor. This review focuses on what has been found of the various ways, natural and experimental, by which HDV particles can be assembled and released. This knowledge has implications for the prevention and treatment of HDV infections, and maybe for an understanding of the origin of HDV.

Citing Articles

Assessment of Response and Safety of Bulevirtide Treatment in Patients with Chronic Delta Virus Infection: The ARISTOTLE Pilot Observational Study.

Rinaldi L, Vigano M, Ciancio A, Caturano A, Messina V, Niro G Viruses. 2025; 17(2).

PMID: 40007006 PMC: 11860205. DOI: 10.3390/v17020251.

vHDvDB 2.0: Database and Group Comparison Server for Hepatitis Delta Virus.

Lee C, Lau Y, Liang Y, Hsian Y, Lin C, Wu H Viruses. 2024; 16(8).

PMID: 39205227 PMC: 11359145. DOI: 10.3390/v16081254.

Hepatitis C Virus as a Possible Helper Virus in Human Hepatitis Delta Virus Infection.

Crobu M, Ravanini P, Impaloni C, Martello C, Bargiacchi O, Di Domenico C Viruses. 2024; 16(6).

PMID: 38932284 PMC: 11209499. DOI: 10.3390/v16060992.

Clinical profile and parameters of patients monoinfected with HBV and infected with HDV in Western Amazon.

Castro E Silva E, Roca T, Passos-Silva A, Borzacov L, Oliveira A, Queiroz J Heliyon. 2024; 10(10):e31065.

PMID: 38803893 PMC: 11128886. DOI: 10.1016/j.heliyon.2024.e31065.

Management of autoimmune hepatitis induced by hepatitis delta virus.

Gigi E, Lagopoulos V, Liakos A World J Gastroenterol. 2024; 30(8):799-805.

PMID: 38516234 PMC: 10950643. DOI: 10.3748/wjg.v30.i8.799.

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