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Fungal Infections in Humans: the Silent Crisis

Overview
Journal Microb Cell
Specialty Microbiology
Date 2020 Jun 18
PMID 32548176
Citations 105
Authors
Katharina Kainz
Maria A Bauer
Frank Madeo
Didac Carmona-Gutierrez
Affiliations
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Abstract

Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in approximately 1.7 million deaths per year. Alarmingly, these numbers are continuously on the rise with a number of social and medical developments during the past decades that have abetted the spread of fungal infections. Additionally, the long-term therapeutic application and prophylactic use of antifungal drugs in high-risk patients have promoted the emergence of (multi)drug-resistant fungi, including the extremely virulent strain . Hence, fungal infections are already a global threat that is becoming increasingly severe. In this article, we underline the importance of more and effective research to counteract fungal infections and their consequences.

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