Natural Skin-whitening Compounds for the Treatment of Melanogenesis (Review)

Overview

Journal Exp Ther Med

Specialty Pathology

Date 2020 Jun 9

PMID 32509007

Citations 65

Authors

Wenhui Qian

Wenya Liu

Dong Zhu

Yanli Cao

Anfu Tang

Guangming Gong

Hua Su

Affiliations

Soon will be listed here.

Abstract

Melanogenesis is the process for the production of melanin, which is the primary cause of human skin pigmentation. Skin-whitening agents are commercially available for those who wish to have a lighter skin complexions. To date, although numerous natural compounds have been proposed to alleviate hyperpigmentation, insufficient attention has been focused on potential natural skin-whitening agents and their mechanism of action from the perspective of compound classification. In the present article, the synthetic process of melanogenesis and associated core signaling pathways are summarized. An overview of the list of natural skin-lightening agents, along with their compound classifications, is also presented, where their efficacy based on their respective mechanisms of action on melanogenesis is discussed.

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