» Articles » PMID: 32498430

The Impact of Diet on Microbiota Evolution and Human Health. Is Diet an Adequate Tool for Microbiota Modulation?

Overview
Journal Nutrients
Date 2020 Jun 6
PMID 32498430
Citations 22
Authors
Affiliations
Soon will be listed here.
Abstract

The human microbiome is emerging as an interesting field in research into the prevention of health problems and recovery from illness in humans. The complex ecosystem formed by the microbiota is continuously interacting with its host and the environment. Diet could be assumed to be one of the most prominent factors influencing the microbiota composition. Nevertheless, and in spite of numerous strategies proposed to modulate the human microbiota through dietary means, guidelines to achieve this goal have yet to be established. This review assesses the correlation between social and dietary changes over the course of human evolution and the adaptation of the human microbiota to those changes. In addition, it discusses the main dietary strategies for modulating the microbiota and the difficulties of putting them properly into practice.

Citing Articles

Shaping the human gut microbiota: The role of canine companionship, lifestyle choices, and sp.

Pavlickova Z, Pafco B, Ilik V, Andersen L, Jirku M, Brozova K One Health. 2025; 20:100979.

PMID: 39944406 PMC: 11815985. DOI: 10.1016/j.onehlt.2025.100979.


Health-Improving Effects of Polyphenols on the Human Intestinal Microbiota: A Review.

Nemzer B, Al-Taher F, Kalita D, Yashin A, Yashin Y Int J Mol Sci. 2025; 26(3).

PMID: 39941107 PMC: 11818678. DOI: 10.3390/ijms26031335.


Mechanisms and Therapeutic Potential of Key Anti-inflammatory Metabiotics: Trans-Vaccenic Acid, Indole-3-Lactic Acid, Thiamine, and Butyric Acid.

Cristina M, Elizabeth B, Jose R, Berenice P, Diego Z, Luis C Probiotics Antimicrob Proteins. 2025; .

PMID: 39921846 DOI: 10.1007/s12602-025-10475-9.


Key features and guidelines for the application of microbial alpha diversity metrics.

Cassol I, Ibanez M, Bustamante J Sci Rep. 2025; 15(1):622.

PMID: 39753610 PMC: 11698868. DOI: 10.1038/s41598-024-77864-y.


Metabolic interactions shape emergent biofilm structures in a conceptual model of gut mucosal bacterial communities.

Valiei A, Dickson A, Aminian-Dehkordi J, Mofrad M NPJ Biofilms Microbiomes. 2024; 10(1):99.

PMID: 39358363 PMC: 11447261. DOI: 10.1038/s41522-024-00572-y.


References
1.
Versalovic J . The human microbiome and probiotics: implications for pediatrics. Ann Nutr Metab. 2013; 63 Suppl 2:42-52. DOI: 10.1159/000354899. View

2.
Hanski I, von Hertzen L, Fyhrquist N, Koskinen K, Torppa K, Laatikainen T . Environmental biodiversity, human microbiota, and allergy are interrelated. Proc Natl Acad Sci U S A. 2012; 109(21):8334-9. PMC: 3361383. DOI: 10.1073/pnas.1205624109. View

3.
Flint H, Duncan S, Scott K, Louis P . Links between diet, gut microbiota composition and gut metabolism. Proc Nutr Soc. 2014; 74(1):13-22. DOI: 10.1017/S0029665114001463. View

4.
Sonnenburg E, Smits S, Tikhonov M, Higginbottom S, Wingreen N, Sonnenburg J . Diet-induced extinctions in the gut microbiota compound over generations. Nature. 2016; 529(7585):212-5. PMC: 4850918. DOI: 10.1038/nature16504. View

5.
Statovci D, Aguilera M, MacSharry J, Melgar S . The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces. Front Immunol. 2017; 8:838. PMC: 5532387. DOI: 10.3389/fimmu.2017.00838. View