Effect of Bupivacaine Versus Lidocaine Local Anesthesia on Postoperative Pain Reduction in Single-port Access Laparoscopic Adnexal Surgery Using Propensity Score Matching
Overview
Authors
Affiliations
Objective: The umbilicus is a single, painful incisional site on the abdomen during trans-umbilical single-port access laparoscopic surgery. Previously, we found that periumbilical lidocaine could reduce postoperative pain. This study aimed to compare the efficacy of bupivacaine and lidocaine in reducing pain.
Methods: We performed a retrospective analysis in a study group (Bupivacaine group, 100 patients who received periumbilical infiltration of bupivacaine before their incisional site repair completion) and control group (Lidocaine group, 100 patients who received lidocaine at their incisional site repair completion). We compared postoperative pain based on the numerical rating scale (NRS) between propensity score-matched Bupivacaine-treated (n=50) and Lidocaine-treated (n=50) patients.
Results: The postoperative pain scores based on the NRS were not significantly different between the 2 groups until 12 hours post-operation. However, 24 hours post-operation, the Bupivacaine group showed significantly lower pain than the Lidocaine group (24 hours, 1.76±1.07 vs. 2.53±1.11 NRS, <0.001; 48 hours, 0.84±0.85 vs. 2.16±0.85 NRS, <0.001).
Conclusion: Periumbilical infiltration of bupivacaine has a longer acting efficacy on reducing postoperative surgical pain than that of lidocaine.
Eoh K, Ahn J, Park J, Park S, Cho Y, Song S BMC Womens Health. 2025; 25(1):83.
PMID: 39994702 PMC: 11849393. DOI: 10.1186/s12905-025-03604-7.
Kang J, Seo Y, Lee H, Kim W, Paik E J Clin Med. 2024; 13(19).
PMID: 39407778 PMC: 11477422. DOI: 10.3390/jcm13195718.
Kang J, Lee K, Heo Y, Kim W, Paik E Front Med (Lausanne). 2023; 10:1199428.
PMID: 37476613 PMC: 10354268. DOI: 10.3389/fmed.2023.1199428.
Seon K, Lee Y, Lee J, Nam E, Kim S, Kim Y Sci Rep. 2023; 13(1):11752.
PMID: 37474581 PMC: 10359395. DOI: 10.1038/s41598-023-37659-z.
Application Effect of Computer-Assisted Local Anesthesia in Patient Operation.
Hao Y, Zhang Z, Meng Y Contrast Media Mol Imaging. 2021; 2021:8643867.
PMID: 34867116 PMC: 8605904. DOI: 10.1155/2021/8643867.