Remifentanil and Sevoflurane Based Anesthesia Combined with Bilateral Erector Spinae Plane Block in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery

Overview

Journal Wideochir Inne Tech Maloinwazyjne

Publisher Termedia

Date 2020 Jun 4

PMID 32489496

Citations 8

Authors

Arkadiusz Kurowicki

Michal Borys

Slawomir Zurek

Beata Horeczy

Boguslaw Gaweda

Bartlomiej Belina

Bozena Trojnar

Bogumila Woloszczuk-Gebicka

Justyna Sejboth

Miroslaw Czuczwar

Kazimierz Widenka

Affiliations

Soon will be listed here.

Abstract

Introduction: Working on the institutional Enhanced Recovery After Surgery (ERAS Cardio) protocol for off-pump coronary artery bypass graft surgery (OP-CABG) we have noticed that patients treated according to the modified anesthesia protocol had not only significantly shorter time of respiratory support and intensive care unit stay but also lower postoperative troponin T concentration than patients who had standard fentanyl/sevoflurane-based anesthesia.

Aim: To compare the perioperative course of patients undergoing OP-CABG surgery and receiving standard fentanyl/sevoflurane anesthesia and those anesthetized according to the institutional ERAS Cardio protocol with remifentanil, sevoflurane, and bilateral extensor spinae plane (ESP) block.

Material And Methods: Design: a prospective, open-label, observational study performed in a tertiary health center. Participants: 30 consecutive patients undergoing off-pump coronary bypass graft surgery. Interventions: 15 patients had standard anesthesia with etomidate, fentanyl, and rocuronium for induction and fentanyl/sevoflurane for maintenance (standard group); 15 others had bilateral single shot ESP block, then etomidate, remifentanil and rocuronium for induction, and remifentanil/sevoflurane for maintenance of anesthesia.

Results: Median time to extubation was 7.6 (5.5-12.5) h and 1.7 (1-3.25) h in "standard care" and ERAS groups, respectively (p = 0.00002). Length of stay in the intensive care unit was also shorter for patients in the ERAS group 20.5 (18-24) vs. 48 (42-48) h (p = 0.00001). Troponin concentration increased to a lesser extent in patients from the ERAS group: an increase of 151.8 (71.9-174.3) ng/ml vs. 253.8 (126.6-373.1) ng/ml, p = 0.008.

Conclusions: Remifentanil/sevoflurane anesthesia combined with bilateral ESP block shortens mechanical ventilation time and ICU stay, and decreases postoperative troponin-T concentration in patients undergoing off-pump coronary bypass graft surgery.

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