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SARS-CoV-2: the Emergence of a Viral Pathogen Causing Havoc on Human Existence

Overview
Journal J Genet
Specialty Genetics
Date 2020 Jun 3
PMID 32482926
Citations 9
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Abstract

Coronavirus disease 2019 was first reported from Wuhan district of China and has spread to 210 countries across the world claiming over 97,602 human lives as on 10 April 2020 by 21:06 pm. Currently, there is no specific treatment for this virus and the treatment is mainly relied on controlling symptoms. Here we discuss our current understanding of SARS-CoV-2 with respect to its receptor recognition and how this knowledge could be useful in treatment using clinically known inhibitory drugs. We have also discussed the diagnosis, treatment and preventive measures that are currently being employed for controlling further spread of the virus.

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References
1.
Chan J, Yuan S, Kok K, To K, Chu H, Yang J . A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020; 395(10223):514-523. PMC: 7159286. DOI: 10.1016/S0140-6736(20)30154-9. View

2.
Mubarak A, Alturaiki W, Hemida M . Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Infection, Immunological Response, and Vaccine Development. J Immunol Res. 2019; 2019:6491738. PMC: 6476043. DOI: 10.1155/2019/6491738. View

3.
Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y . Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med. 2020; 382(13):1199-1207. PMC: 7121484. DOI: 10.1056/NEJMoa2001316. View

4.
Andersen K, Rambaut A, Lipkin W, Holmes E, Garry R . The proximal origin of SARS-CoV-2. Nat Med. 2020; 26(4):450-452. PMC: 7095063. DOI: 10.1038/s41591-020-0820-9. View

5.
Keidar S, Kaplan M, Gamliel-Lazarovich A . ACE2 of the heart: From angiotensin I to angiotensin (1-7). Cardiovasc Res. 2006; 73(3):463-9. DOI: 10.1016/j.cardiores.2006.09.006. View